PMID- 24942223
OWN - NLM
STAT- MEDLINE
DCOM- 20160303
LR  - 20150606
IS  - 2047-4881 (Electronic)
IS  - 2047-4873 (Linking)
VI  - 22
IP  - 7
DP  - 2015 Jul
TI  - Efficacy and safety of functional electrical stimulation of lower limb muscles in 
      elderly patients with chronic heart failure: A pilot study.
PG  - 831-6
LID - 10.1177/2047487314540546 [doi]
AB  - BACKGROUND: Exercise training is an established modality in chronic heart 
      failure. Functional electrical stimulation (FES) is an effective alternative mode 
      of training in patients unwilling or unable to exercise; however, it has not been 
      investigated in elderly patients. We sought to investigate the effects of FES on 
      functional status, quality of life, emotional status and endothelial function in 
      chronic heart failure patients aged 70 years or higher. METHODS: Thirty patients 
      with stable systolic chronic heart failure (mean age 75 +/- 3 years, New York Heart 
      Association (NYHA) class II/III, 37%/63%) randomly underwent a six-week FES 
      training programme or placebo. Questionnaires addressing quality of life (Kansas 
      City Cardiomyopathy Questionnaire (KCCQ), functional and overall) and emotional 
      stress (Zung self-rating depression scale (SDS), Beck Depression Inventory 
      (BDI)), as well as endothelial function (flow-mediated dilatation) were assessed 
      at baseline and upon protocol completion. RESULTS: A significant improvement in 
      NYHA class (p=0.005), KCCQ-functional (F=68.6, p for interaction<0.001), 
      KCCQ-overall (F=66.9, p<0.001), BDI (F=66.3, p<0.001) and Zung SDS (F=95.1, 
      p<0.001) was observed in the FES group compared to placebo. Patients in the FES 
      group also had a significant increase in flow-mediated dilatation compared with 
      placebo (F=59.1, p<0.01). FES-induced per cent change in flow-mediated dilatation 
      was significantly correlated with respective per cent change in KCCQ functional 
      (r=0.386, p=0.039). CONCLUSION: In this pilot study, FES effectively improved 
      functional status, quality of life, motional stress and endothelial function in 
      elderly chronic heart failure patients and warrants further investigation in this 
      particular group of patients.
CI  - (c) The European Society of Cardiology 2014 Reprints and permissions: 
      sagepub.co.uk/journalsPermissions.nav.
FAU - Parissis, John
AU  - Parissis J
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Karavidas, Apostolos
AU  - Karavidas A
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Farmakis, Dimitrios
AU  - Farmakis D
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece dimitrios_farmakis@yahoo.com.
FAU - Papoutsidakis, Nikolaos
AU  - Papoutsidakis N
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Matzaraki, Vassiliki
AU  - Matzaraki V
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Arapi, Sofia
AU  - Arapi S
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Potamitis, Nikolaos
AU  - Potamitis N
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Nikolaou, Maria
AU  - Nikolaou M
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Paraskevaidis, Ioannis
AU  - Paraskevaidis I
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Ikonomidis, Ignatios
AU  - Ikonomidis I
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Pyrgakis, Vlassios
AU  - Pyrgakis V
AD  - Department of Cardiology, G Gennimatas Hospital, Athens, Greece.
FAU - Kremastinos, Dimitrios
AU  - Kremastinos D
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Lekakis, John
AU  - Lekakis J
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
FAU - Filippatos, Gerasimos
AU  - Filippatos G
AD  - Heart Failure Unit, Department of Cardiology, Attikon University Hospital, 
      Athens, Greece.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20140618
PL  - England
TA  - Eur J Prev Cardiol
JT  - European journal of preventive cardiology
JID - 101564430
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Brachial Artery/physiopathology
MH  - Chronic Disease
MH  - Electric Stimulation Therapy/adverse effects/*methods
MH  - Emotions
MH  - Endothelium, Vascular/physiopathology
MH  - Exercise Tolerance
MH  - Female
MH  - Greece
MH  - Heart Failure/diagnosis/physiopathology/psychology/*therapy
MH  - Humans
MH  - Lower Extremity
MH  - Male
MH  - *Muscle Contraction
MH  - Muscle, Skeletal/blood supply/*innervation
MH  - Pilot Projects
MH  - Quality of Life
MH  - Recovery of Function
MH  - Regional Blood Flow
MH  - Surveys and Questionnaires
MH  - Time Factors
MH  - Treatment Outcome
MH  - Vasodilation
OTO - NOTNLM
OT  - Heart failure
OT  - elderly
OT  - exercise
OT  - functional electrical stimulation
OT  - rehabilitation
EDAT- 2014/06/20 06:00
MHDA- 2016/03/05 06:00
CRDT- 2014/06/20 06:00
PHST- 2014/03/19 00:00 [received]
PHST- 2014/06/02 00:00 [accepted]
PHST- 2014/06/20 06:00 [entrez]
PHST- 2014/06/20 06:00 [pubmed]
PHST- 2016/03/05 06:00 [medline]
AID - 2047487314540546 [pii]
AID - 10.1177/2047487314540546 [doi]
PST - ppublish
SO  - Eur J Prev Cardiol. 2015 Jul;22(7):831-6. doi: 10.1177/2047487314540546. Epub 
      2014 Jun 18.