PMID- 24948940 OWN - NLM STAT- MEDLINE DCOM- 20150204 LR - 20211021 IS - 1678-4405 (Electronic) IS - 1517-8382 (Print) IS - 1517-8382 (Linking) VI - 45 IP - 1 DP - 2014 TI - Paracoccidioidomycosis in southern Rio Grande do Sul: a retrospective study of histopathologically diagnosed cases. PG - 243-7 AB - Paracoccidioidomycosis (PCM) is a systemic mycosis caused by the fungus Paracoccidioides brasiliensis and is endemic to Brazil. The aim of this study was to perform a retrospective analysis of the PCM cases in the countryside south of Rio Grande do Sul, Brazil. The files from four histopathology laboratories located in the city of Pelotas were obtained, and all of the epidemiological and clinical data from the PCM diagnosed cases were collected for analysis. A total of 123 PCM cases diagnosed between 1966 and 2009 were selected. Of these patients, 104 (84.5%) were male, and 17 were female. The patients ranged from 02 to 92 years of age. Fifty-two cases (41.9%) were obtained from the oral pathology laboratory, and the remaining 71 cases (58.1%) were obtained from the three general pathology laboratories. Of all of the patients studied, 65.2% lived in rural zones and worked in agriculture or other related fields. Data on the evolution of this disease was available for 43 cases, and the time frame ranged from 20 to 2920 days (mean = 572.3 days). An accurate diagnosis performed in less than 30 days only occurred in 21% of the cases. PCM is endemic to the countryside of Rio Grande do Sul. Therefore, it is recommended that PCM be included as a differential diagnosis, mainly for individuals between 30 and 60 years of age, living in rural zones and who have respiratory signs and associated-oropharyngeal lesions. FAU - de Souza, Silvana Pereira AU - de Souza SP AD - Faculdade de Odontologia Universidade Federal de Pelotas PelotasRS Brazil. FAU - Jorge, Valeria Magalhaes AU - Jorge VM AD - Faculdade de Odontologia Universidade Federal de Pelotas PelotasRS Brazil ; Santa Casa de Misericordia de Pelotas PelotasRS Brazil. FAU - Xavier, Melissa Orzechowski AU - Xavier MO AD - Faculdade de Medicina Universidade Federal do Rio Grande Rio GrandeRS Brazil ; Programa de Pos-Graduacao em Ciencias da Saude Universidade Federal do Rio Grande Rio GrandeRS Brazil. LA - eng PT - Journal Article DEP - 20140519 PL - Brazil TA - Braz J Microbiol JT - Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] JID - 101095924 SB - IM MH - Adolescent MH - Adult MH - Age Distribution MH - Aged MH - Aged, 80 and over MH - Brazil/epidemiology MH - Child MH - Child, Preschool MH - Endemic Diseases MH - Female MH - Histocytochemistry MH - Humans MH - Infant MH - Male MH - Middle Aged MH - Paracoccidioides/*isolation & purification MH - Paracoccidioidomycosis/*epidemiology/pathology MH - Retrospective Studies MH - Rural Population MH - Sex Distribution MH - Young Adult PMC - PMC4059305 OTO - NOTNLM OT - Paracoccidioides brasiliensis OT - epidemiology OT - systemic mycosis EDAT- 2014/06/21 06:00 MHDA- 2015/02/05 06:00 PMCR- 2014/06/19 CRDT- 2014/06/21 06:00 PHST- 2012/05/28 00:00 [received] PHST- 2013/09/09 00:00 [accepted] PHST- 2014/06/21 06:00 [entrez] PHST- 2014/06/21 06:00 [pubmed] PHST- 2015/02/05 06:00 [medline] PHST- 2014/06/19 00:00 [pmc-release] AID - bjm-45-243 [pii] AID - 10.1590/s1517-83822014000100035 [doi] PST - epublish SO - Braz J Microbiol. 2014 May 19;45(1):243-7. doi: 10.1590/s1517-83822014000100035. eCollection 2014.