PMID- 24949575
OWN - NLM
STAT- MEDLINE
DCOM- 20150819
LR  - 20181202
IS  - 1525-5069 (Electronic)
IS  - 1525-5050 (Linking)
VI  - 37
DP  - 2014 Aug
TI  - Impact of family support on psychiatric disorders and seizure control in patients 
      with juvenile myoclonic epilepsy.
PG  - 7-10
LID - S1525-5050(14)00194-2 [pii]
LID - 10.1016/j.yebeh.2014.05.020 [doi]
AB  - OBJECTIVE: Psychiatric disorders (PDs) are frequently observed in patients with 
      juvenile myoclonic epilepsy (JME). In this study, we aimed to assess factors 
      associated with PDs in patients with JME. METHODS: Retrospective analysis of data 
      of 90 consecutive patients with JME was performed. Assessment of DSM-IV Axis I 
      clinical disorders was done using Structured Clinical Interview for Axis I. 
      Diagnosis of PDs is made when the score exceeds the threshold provided by the 
      DSM-IV. We also applied the Global Assessment of Functioning (GAF) scale which is 
      part of the multiaxial evaluation of the DSM-IV (Axis-V). Using seizure frequency 
      score at presentation, we classified subjects into controlled and uncontrolled 
      groups. RESULTS: In the current cohort, 29 (32.2%) patients were diagnosed with 
      PDs. Fewer patients with PDs had family support (48.3% vs. 83.6%; p=0.001). 
      Lifetime prevalence of PDs was higher among patients with current PDs (96.6% vs. 
      18.0%; p<0.0001). Subthreshold illness was not different between the groups 
      (17.2% vs. 27.9%; p=0.204). Mean GAF was higher in patients without PDs than in 
      patients with PDs (89.19+/-6.92 vs. 64.22+/-9.76; p<0.0001). Patients with PDs had 
      lower seizure control (7.8% vs. 73.1%; p<0.0001) compared with patients without 
      PDs. Logistic regression analysis for factors associated with diagnosis of PDs 
      revealed that none of the factors significantly affected the odds of seizure 
      control. Patients with lack of family support had poor seizure control (0% vs. 
      36.9%; p<0.0001); 51.7% of patients with JME with PDs reported lack of family 
      support. Patients with family support had lower lifetime prevalence of PDs (30.8% 
      vs. 76.0%; p<0.0001), whereas patients with JME without family support had lower 
      levels of education (8.0% vs. 35.4%; p=0.009). CONCLUSION: Lack of family support 
      is associated with poor seizure control and higher incidence of PDs in patients 
      with JME. Lack of family support increases neither the odds of PDs nor seizure 
      control.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Jayalakshmi, Sita
AU  - Jayalakshmi S
AD  - Department of Neurology, Krishna Institute of Medical Sciences, Minister Road, 
      Secunderabad-03, Andhra Pradesh, India. Electronic address: sita_js@hotmail.com.
FAU - Padmaja, Gaddamanugu
AU  - Padmaja G
AD  - Department of Neurology, Nizam's Institute of Medical Sciences, Punjagutta, 
      Hyderabad, Andhra Pradesh, India.
FAU - Vooturi, Sudhindra
AU  - Vooturi S
AD  - Department of Neurology, Krishna Institute of Medical Sciences, Minister Road, 
      Secunderabad-03, Andhra Pradesh, India.
FAU - Bogaraju, Anand
AU  - Bogaraju A
AD  - Institute of Mental Health, Hyderabad, India.
FAU - Surath, Mohandas
AU  - Surath M
AD  - Department of Neurology, Krishna Institute of Medical Sciences, Minister Road, 
      Secunderabad-03, Andhra Pradesh, India.
LA  - eng
PT  - Journal Article
DEP - 20140618
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
SB  - IM
MH  - Adult
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Male
MH  - Mental Disorders/epidemiology/*etiology
MH  - Middle Aged
MH  - Myoclonic Epilepsy, Juvenile/complications/*diagnosis/epidemiology
MH  - Psychiatric Status Rating Scales
MH  - Retrospective Studies
MH  - Seizures/complications/epidemiology/*prevention & control
MH  - *Social Support
OTO - NOTNLM
OT  - Family support
OT  - Juvenile myoclonic epilepsy
OT  - Psychiatric comorbidities
OT  - Seizure control
EDAT- 2014/06/21 06:00
MHDA- 2015/08/20 06:00
CRDT- 2014/06/21 06:00
PHST- 2014/05/06 00:00 [received]
PHST- 2014/05/18 00:00 [revised]
PHST- 2014/05/23 00:00 [accepted]
PHST- 2014/06/21 06:00 [entrez]
PHST- 2014/06/21 06:00 [pubmed]
PHST- 2015/08/20 06:00 [medline]
AID - S1525-5050(14)00194-2 [pii]
AID - 10.1016/j.yebeh.2014.05.020 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2014 Aug;37:7-10. doi: 10.1016/j.yebeh.2014.05.020. Epub 2014 Jun 
      18.