PMID- 24955197 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140623 LR - 20211021 IS - 1940-5901 (Print) IS - 1940-5901 (Electronic) IS - 1940-5901 (Linking) VI - 7 IP - 4 DP - 2014 TI - Total osteocalcin in serum predicts testosterone level in male type 2 diabetes mellitus. PG - 1145-9 AB - OBJECTIVE: To investigate the relationship between total osteocalcin (total OC) and testosterone level in the serum of male patients with type 2 diabetes mellitus (T2DM). METHODS: 98 male T2DM were recruited in our cross-section study. Their anthropometric parameters were measured and body mass index (BMI) was calculated. Serum markers including glucose, insulin, HbA1c, testosterone, total OC and other bone metabolic markers were examined. Simple Pearson correlation and multiple regression analysis were performed. RESULTS: Poor level of glucose control was found in the patients (HbA1c 9.19+/-2.53 and FPG 8.20+/-2.98). In simple Pearson correlation, total OC was positively related with testosterone (r=0.236, P=0.019), and this relation still existed after considering all the parameters of the patients (Model 1, 2 and 3). CONCLUSION: In male patients with T2DM, total OC was positively correlated with testosterone, so total OC might predict the testosterone level in the serum. FAU - Cui, Ran AU - Cui R AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Su, Bin AU - Su B AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Sheng, Chunjun AU - Sheng C AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Cheng, Xiaoyun AU - Cheng X AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Yang, Peng AU - Yang P AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Bu, Le AU - Bu L AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Li, Hong AU - Li H AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Wang, Jiying AU - Wang J AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. FAU - Sheng, Hui AU - Sheng H AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China ; Advanced Institute of Translational Medicine, Tongji University Shanghai 200092, China. FAU - Qu, Shen AU - Qu S AD - Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University School of Medicine Shanghai 200072, China. LA - eng PT - Journal Article DEP - 20140415 PL - United States TA - Int J Clin Exp Med JT - International journal of clinical and experimental medicine JID - 101471010 PMC - PMC4057876 OTO - NOTNLM OT - Osteocalcin OT - testosterone OT - type 2 diabetes mellitus OT - undercarboxylated osteocalcin EDAT- 2014/06/24 06:00 MHDA- 2014/06/24 06:01 PMCR- 2014/04/15 CRDT- 2014/06/24 06:00 PHST- 2014/02/15 00:00 [received] PHST- 2014/03/28 00:00 [accepted] PHST- 2014/06/24 06:00 [entrez] PHST- 2014/06/24 06:00 [pubmed] PHST- 2014/06/24 06:01 [medline] PHST- 2014/04/15 00:00 [pmc-release] PST - epublish SO - Int J Clin Exp Med. 2014 Apr 15;7(4):1145-9. eCollection 2014.