PMID- 24968083
OWN - NLM
STAT- MEDLINE
DCOM- 20141003
LR  - 20161125
IS  - 1096-0953 (Electronic)
IS  - 0013-9351 (Linking)
VI  - 133
DP  - 2014 Aug
TI  - Prenatal exposure to persistent organic pollutants and polybrominated diphenyl 
      ethers in 10 Caribbean countries.
PG  - 211-9
LID - S0013-9351(14)00175-3 [pii]
LID - 10.1016/j.envres.2014.05.021 [doi]
AB  - Prenatal exposures to legacy persistent organic pollutants (POPs) such as 
      polychlorinated biphenyls (PCBs) and dioxin-like compounds (DLC), as well as 
      polybrominated diphenyl ethers (PBDE), were analyzed in pregnant women from 10 
      Caribbean countries. A total of 438 samples were collected and descriptive 
      statistics calculated and compared to comparable Canadian Health Measure Survey 
      (CHMS) and U.S. National Health and Nutritional Examination Survey (NHANES) 
      datasets. Maternal POPs blood concentrations were found to be generally 
      relatively low in the Caribbean samples compared with the U.S. and Canada 
      datasets. Evidence of exposure to DLC and PBDE was established. DLC levels ranged 
      from a geometric mean low of 3.96 pg/g lipids in Antigua and Barbuda to a high of 
      11.4 pg/g lipids in St. Lucia. Several of the PBDEs (15, 17, 25, 28, 33, 100) 
      were detected in less than 60% of the country' samples. For PBDE-47, 
      significantly higher levels were found in Bermuda, while Jamaica recorded a 
      significantly low level. The overall calculated concentration of PBDE-47 for the 
      Caribbean (5.33 mug/kg lipids) was significantly lower than the concentrations 
      measured for the U.S. (10.83 mug/kg lipids) and Canada (23.90 mug/kg lipids). This 
      study confirms that prenatal expose to multiple environmental chemicals is taking 
      place in the Caribbean and highlights the need to implement surveillance programs 
      that continuously monitor, intervene, and evaluate the levels of these toxic 
      environmental contaminants to ensure that they are reduced as much as possible 
      and that the health risk to humans, in particular the unborn child, are 
      minimized.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Forde, Martin S
AU  - Forde MS
AD  - Department of Public Health & Preventive Medicine, St. George׳s University, St. 
      George׳s, Grenada, West Indies. Electronic address: martinforde@mac.com.
FAU - Dewailly, Eric
AU  - Dewailly E
AD  - Axe Sante des populations et pratiques optimales en sante, Centre de recherche du 
      CHU de Quebec and Universite Laval, Quebec, QC, Canada; Institut national de la 
      sante publique du Quebec, Quebec, QC, Canada.
FAU - Robertson, Lyndon
AU  - Robertson L
AD  - Caribbean EcoHealth Programme (CEHP), Windward Islands Research and Education 
      Foundation (WINDREF), St. George׳s University, Grenada, West Indies.
FAU - Laouan Sidi, Elhadji A
AU  - Laouan Sidi EA
AD  - Axe Sante des populations et pratiques optimales en sante, Centre de recherche du 
      CHU de Quebec and Universite Laval, Quebec, QC, Canada.
FAU - Cote, Suzanne
AU  - Cote S
AD  - Axe Sante des populations et pratiques optimales en sante, Centre de recherche du 
      CHU de Quebec and Universite Laval, Quebec, QC, Canada.
FAU - Dumas, Pierre
AU  - Dumas P
AD  - Institut national de la sante publique du Quebec, Quebec, QC, Canada.
FAU - Ayotte, Pierre
AU  - Ayotte P
AD  - Axe Sante des populations et pratiques optimales en sante, Centre de recherche du 
      CHU de Quebec and Universite Laval, Quebec, QC, Canada; Institut national de la 
      sante publique du Quebec, Quebec, QC, Canada.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140624
PL  - Netherlands
TA  - Environ Res
JT  - Environmental research
JID - 0147621
RN  - 0 (Environmental Pollutants)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Polychlorinated Dibenzodioxins)
SB  - IM
MH  - Adult
MH  - Caribbean Region
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Halogenated Diphenyl Ethers/*blood
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*blood
MH  - *Maternal Exposure/statistics & numerical data
MH  - Nutrition Surveys/methods
MH  - Polychlorinated Dibenzodioxins/*blood
MH  - Population Surveillance
MH  - Pregnancy
MH  - Young Adult
OTO - NOTNLM
OT  - Caribbean
OT  - Dioxins
OT  - Persistent organic pollutants
OT  - Polybrominated diphenyl ethers
OT  - Prenatal exposure
EDAT- 2014/06/27 06:00
MHDA- 2014/10/04 06:00
CRDT- 2014/06/27 06:00
PHST- 2014/02/28 00:00 [received]
PHST- 2014/05/06 00:00 [revised]
PHST- 2014/05/20 00:00 [accepted]
PHST- 2014/06/27 06:00 [entrez]
PHST- 2014/06/27 06:00 [pubmed]
PHST- 2014/10/04 06:00 [medline]
AID - S0013-9351(14)00175-3 [pii]
AID - 10.1016/j.envres.2014.05.021 [doi]
PST - ppublish
SO  - Environ Res. 2014 Aug;133:211-9. doi: 10.1016/j.envres.2014.05.021. Epub 2014 Jun 
      24.