PMID- 24970361
OWN - NLM
STAT- MEDLINE
DCOM- 20141110
LR  - 20140728
IS  - 1873-2542 (Electronic)
IS  - 0378-1135 (Linking)
VI  - 172
IP  - 3-4
DP  - 2014 Aug 27
TI  - Detection and distribution of torque teno sus virus 1 in porcine reproductive and 
      respiratory syndrome virus positive/negative pigs.
PG  - 367-70
LID - S0378-1135(14)00244-2 [pii]
LID - 10.1016/j.vetmic.2014.05.008 [doi]
AB  - To investigate the detection rate and distribution of torque teno sus virus 1 
      (TTSuV1) in porcine reproductive and respiratory syndrome virus (PRRSV) 
      positive/negative pigs, 2384 pathological tissues samples collected from 6 
      provinces of Eastern China from 2010 to 2013 were amplified using previously 
      published PRRSV and TTSuV1 primers. The presence and viral load of TTSuV1 were 
      investigated in a wide range of samples from 5 PRRSV positive/negative 4-week-old 
      pigs by real-time TaqMan PCR. TTSuV1 was detected in 65.3% of 1115 PRRSV-positive 
      samples, and 47.2% of 1269 negative samples. Viral DNA was most commonly detected 
      in the immune organs, including spleen, lung, pancreas, and mesenteric and 
      inguinal lymph nodes, followed by serum, liver, kidney, trachea, anal swabs, 
      nasal swabs and sex glands of PRRSV-positive or negative pigs. TTSuV1 DNA loads 
      in PRRSV-positive pigs increased from 2 to 5 times in almost all the 
      corresponding parts compared with PRRSV-negative pigs. Statistical analysis 
      showed that PRRSV may have a synergistic effect with TTSuV1, and promote the 
      replication and proliferation of TTSuV1.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Zhang, Zhicheng
AU  - Zhang Z
AD  - Department of Animal Science and Technology, Jinling Institution of Technology, 
      Nanjing 210038, China. Electronic address: andzzc@126.com.
FAU - Wang, Yang
AU  - Wang Y
AD  - College of Animal Science and Technology, Henan University of Science and 
      Technology, Luoyang 471003, China.
FAU - Dai, Wei
AU  - Dai W
AD  - Key Laboratory of Zoonoses of Anhui Province, Anhui Agricultural University, 
      Hefei 230036, China.
FAU - Dai, Dingzhen
AU  - Dai D
AD  - Department of Animal Science and Technology, Jinling Institution of Technology, 
      Nanjing 210038, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140513
PL  - Netherlands
TA  - Vet Microbiol
JT  - Veterinary microbiology
JID - 7705469
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Animals
MH  - China/epidemiology
MH  - Coinfection
MH  - DNA Virus Infections/complications/epidemiology/*veterinary/virology
MH  - DNA, Viral/analysis
MH  - Female
MH  - Lung/virology
MH  - Male
MH  - Porcine Reproductive and Respiratory Syndrome/epidemiology/*virology
MH  - Porcine respiratory and reproductive syndrome virus/*isolation & purification
MH  - Pregnancy
MH  - Real-Time Polymerase Chain Reaction
MH  - Swine
MH  - Swine Diseases/*virology
MH  - Torque teno virus/classification/*isolation & purification
MH  - Viral Load
OTO - NOTNLM
OT  - Porcine reproductive and respiratory syndrome virus
OT  - Torque teno sus virus 1
OT  - Virus detection
OT  - Virus distribution
EDAT- 2014/06/28 06:00
MHDA- 2014/11/11 06:00
CRDT- 2014/06/28 06:00
PHST- 2013/08/02 00:00 [received]
PHST- 2014/05/03 00:00 [revised]
PHST- 2014/05/05 00:00 [accepted]
PHST- 2014/06/28 06:00 [entrez]
PHST- 2014/06/28 06:00 [pubmed]
PHST- 2014/11/11 06:00 [medline]
AID - S0378-1135(14)00244-2 [pii]
AID - 10.1016/j.vetmic.2014.05.008 [doi]
PST - ppublish
SO  - Vet Microbiol. 2014 Aug 27;172(3-4):367-70. doi: 10.1016/j.vetmic.2014.05.008. 
      Epub 2014 May 13.