PMID- 24982729 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20140701 LR - 20211021 IS - 2008-2010 (Print) IS - 2008-322X (Electronic) IS - 2008-322X (Linking) VI - 9 IP - 1 DP - 2014 Jan TI - Agreement of two different spectral domain optical coherence tomography instruments for retinal nerve fiber layer measurements. PG - 31-7 AB - PURPOSE: To determine the agreement between Spectralis and Cirrus spectral domain optical coherence tomography (SD-OCT) measurements of peripapillary retinal nerve fiber layer (RNFL) thickness. METHODS: Suspected or confirmed cases of glaucoma who met the inclusion criteria underwent peripapillary RNFL thickness measurement using both the Spectralis and Cirrus on the same day within a few minutes. RESULTS: Measurements were performed on 103 eyes of 103 patients with mean age of 50.4+/-17.7 years. Mean RNFL thickness was 89.22+/-15.87 versus 84.54+/-13.68 microm using Spectralis and Cirrus, respectively. The difference between measurements and the average of paired measurements with the two devices showed a significant linear relationship. Bland-Altman plots demonstrated that Spectralis thickness values were systematically larger than that of Cirrus. CONCLUSION: Spectralis OCT generates higher peripapillary RNFL thickness readings as compared to Cirrus OCT; this should be kept in mind when values obtained with different instruments are compared during follow-up. FAU - Faghihi, Hooshang AU - Faghihi H AD - Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran ; Department of Ophthalmology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Hajizadeh, Fedra AU - Hajizadeh F AD - Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran. FAU - Hashemi, Hassan AU - Hashemi H AD - Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran ; Department of Ophthalmology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Khabazkhoob, Mehdi AU - Khabazkhoob M AD - Dezful University of Medical Sciences, Dezful, Iran. LA - eng PT - Journal Article PL - United Arab Emirates TA - J Ophthalmic Vis Res JT - Journal of ophthalmic & vision research JID - 101497643 PMC - PMC4074471 OTO - NOTNLM OT - Glaucoma OT - Optical Coherence Tomography OT - Peripapillary Retinal Nerve Fiber Layer EDAT- 2014/07/02 06:00 MHDA- 2014/07/02 06:01 PMCR- 2014/01/01 CRDT- 2014/07/02 06:00 PHST- 2012/10/22 00:00 [received] PHST- 2013/07/29 00:00 [accepted] PHST- 2014/07/02 06:00 [entrez] PHST- 2014/07/02 06:00 [pubmed] PHST- 2014/07/02 06:01 [medline] PHST- 2014/01/01 00:00 [pmc-release] AID - JOVR-09-031 [pii] PST - ppublish SO - J Ophthalmic Vis Res. 2014 Jan;9(1):31-7.