PMID- 24983856 OWN - NLM STAT- MEDLINE DCOM- 20160515 LR - 20140711 IS - 2040-3372 (Electronic) IS - 2040-3364 (Linking) VI - 6 IP - 15 DP - 2014 Aug 7 TI - Super-resolution fluorescence imaging of biocompatible carbon dots. PG - 8617-23 LID - 10.1039/c4nr01970a [doi] AB - Carbon Dots (CDs) are a new promising type of small (5 nm), biocompatible and multicolor luminescent nanoparticle. Here, we demonstrate super-resolution imaging of CDs at the nanoscale through STimulated Emission Depletion (STED) microscopy. In addition, we report the application of STED for detection of CD localization in both fixed and living cells, achieving a spatial resolution down to 30 nm, far below the diffraction limit, showing great promise for high resolution visualization of cellular dynamics. FAU - Lemenager, Godefroy AU - Lemenager G AD - Istituto Italiano di Tecnologia, Center for Bio-Molecular Nanotechnologies@UniLe, Via Barsanti - 73010, Arnesano (Lecce), Italy. pierpaolo.pompa@iit.it. FAU - De Luca, Elisa AU - De Luca E FAU - Sun, Ya-Ping AU - Sun YP FAU - Pompa, Pier Paolo AU - Pompa PP LA - eng PT - Journal Article PL - England TA - Nanoscale JT - Nanoscale JID - 101525249 RN - 0 (Biocompatible Materials) RN - 7440-44-0 (Carbon) SB - IM MH - Biocompatible Materials/*chemistry MH - Carbon/*chemistry MH - Cell Line, Tumor MH - Cell Survival MH - Dose-Response Relationship, Drug MH - Humans MH - Luminescence MH - MCF-7 Cells MH - Microscopy, Confocal MH - *Microscopy, Fluorescence MH - Nanoparticles/*chemistry MH - Nanotechnology MH - Optics and Photonics MH - Photochemistry EDAT- 2014/07/02 06:00 MHDA- 2016/05/18 06:00 CRDT- 2014/07/02 06:00 PHST- 2014/07/02 06:00 [entrez] PHST- 2014/07/02 06:00 [pubmed] PHST- 2016/05/18 06:00 [medline] AID - 10.1039/c4nr01970a [doi] PST - ppublish SO - Nanoscale. 2014 Aug 7;6(15):8617-23. doi: 10.1039/c4nr01970a.