PMID- 24984458
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150901
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 32
IP  - 3
DP  - 2014 Mar
TI  - [Determination of kepone in water by liquid chromatography-tandem mass 
      spectrometry].
PG  - 211-5
AB  - An analytical procedure for the determination of kepone in water was described. 
      Water samples were extracted by liquid-liquid extraction, and then cleaned-up. 
      Chromatographic separation was performed on an Eclipse plus C18 column (100 mm x 
      2.1 mm, 3.5 microm) with gradient elution using acetonitrile and water at a flow 
      rate of 0.3 mL/min. The target compounds were determined in multiple reaction 
      monitoring (MRM) mode via negative electrospray ionization (ESI(-)) and 
      quantified by isotopic-dilution technique. Results showed that kepone existed as 
      diol form and hemiacetal in acetone/acetonitrile and methanol respectively, the 
      structures of which were confirmed by liquid chromatography-tandem mass 
      spectrometry (LC-MS/MS). Due to the polar nature of kepone, it was difficult to 
      be eluted during clean-up procedure and it may be decomposed during sulfuric acid 
      washing. Therefore, it could not be analyzed together with the other 
      organochlorine pesticides. The calibration curve showed good linearity in the 
      range of 5-100 microg/L with correlation coefficient (r2) of 0.999. The limit of 
      detection was 0.70 ng/L and the limit of quantification was 2.8 ng/L in water. 
      The average recoveries when spiked at 5, 40 and 100 ng/L in water were 
      95.1%-98.9%, and the relative standard deviations (RSDs) were 3.85%-4.72%. The 
      method can be used to the determination of kepone in water due to its high 
      sensitivity, good recovery and reproducibility.
FAU - Zhou, Li
AU  - Zhou L
FAU - Dong, Liang
AU  - Dong L
FAU - Shi, Shuangxin
AU  - Shi S
FAU - Zhang, Lifei
AU  - Zhang L
FAU - Zhang, Xiulan
AU  - Zhang X
FAU - Yang, Wenlong
AU  - Yang W
FAU - Li, Lingling
AU  - Li L
FAU - Huang, Yeru
AU  - Huang Y
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
EDAT- 2014/07/06 06:00
MHDA- 2014/07/06 06:01
CRDT- 2014/07/03 06:00
PHST- 2014/07/03 06:00 [entrez]
PHST- 2014/07/06 06:00 [pubmed]
PHST- 2014/07/06 06:01 [medline]
AID - 10.3724/sp.j.1123.2013.11053 [doi]
PST - ppublish
SO  - Se Pu. 2014 Mar;32(3):211-5. doi: 10.3724/sp.j.1123.2013.11053.