PMID- 24985744
OWN - NLM
STAT- MEDLINE
DCOM- 20150330
LR  - 20221207
IS  - 1532-432X (Electronic)
IS  - 0363-0269 (Linking)
VI  - 38
IP  - 4
DP  - 2014
TI  - Red cell indices and formulas used in differentiation of beta-thalassemia trait from 
      iron deficiency in Thai school children.
PG  - 258-61
LID - 10.3109/03630269.2014.930044 [doi]
AB  - Red cell indices and formulas have been established as simple, fast, and 
      inexpensive means for discrimination between the beta-thalassemia (beta-thal) trait and 
      iron deficiency. However, there were no reports of the diagnostic reliability of 
      different red cell indices and formulas in discrimination of beta-thal trait from 
      iron deficiency in the Thai population. The aim of this study was to examine the 
      diagnostic accuracy of five red cell indices [red blood cell (RBC) count, mean 
      corpuscular volume (MCV), mean corpuscular hemoglobin (Hb) (MCH), mean 
      corpuscular Hb concentration (MCHC), and red cell distribution width (RDW)] and 
      eight formulas (Sirdah, Green & King, RDW Index, Menzler, England & Fraser, 
      Ehsani, Srivastava, and Shine & Lal). Their sensitivity, specificity, positive 
      and negative prognostic value and efficiency, were analyzed in 77 Thai school 
      children, 21 with the beta-thal trait and 56 with iron deficiency. The Sirdah and 
      Srivastava formulas proved to be the most reliable indexes as they had 100.0% 
      sensitivity and negative predictive value, the highest efficiency (97.4%), and 
      the highest Youden's Index value (96.4%). Therefore, these formulas could be used 
      in initial discrimination of the beta-thal trait from iron deficiency in Thai school 
      children.
FAU - Pornprasert, Sakorn
AU  - Pornprasert S
AD  - Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang 
      Mai University , Chiang Mai , Thailand and.
FAU - Panya, Auttapon
AU  - Panya A
FAU - Punyamung, Manoo
AU  - Punyamung M
FAU - Yanola, Jintana
AU  - Yanola J
FAU - Kongpan, Chatpat
AU  - Kongpan C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140702
PL  - England
TA  - Hemoglobin
JT  - Hemoglobin
JID - 7705865
SB  - IM
MH  - Adolescent
MH  - Anemia, Iron-Deficiency/*blood/*diagnosis
MH  - Asian People
MH  - Child
MH  - Diagnosis, Differential
MH  - *Erythrocyte Indices
MH  - Female
MH  - Humans
MH  - Male
MH  - *Students
MH  - beta-Thalassemia/*blood/*diagnosis
OTO - NOTNLM
OT  - Thai school children
OT  - formulas
OT  - iron deficiency
OT  - red cell indices
OT  - beta-Thalassemia (beta-thal)
EDAT- 2014/07/06 06:00
MHDA- 2015/03/31 06:00
CRDT- 2014/07/03 06:00
PHST- 2014/07/03 06:00 [entrez]
PHST- 2014/07/06 06:00 [pubmed]
PHST- 2015/03/31 06:00 [medline]
AID - 10.3109/03630269.2014.930044 [doi]
PST - ppublish
SO  - Hemoglobin. 2014;38(4):258-61. doi: 10.3109/03630269.2014.930044. Epub 2014 Jul 
      2.