PMID- 24994748
OWN - NLM
STAT- MEDLINE
DCOM- 20150121
LR  - 20211021
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2014
DP  - 2014 Jul 3
TI  - Posterior spinal artery aneurysm rupture after 'Ecstasy' abuse.
LID - 10.1136/bcr-2014-011248 [doi]
LID - bcr2014011248
AB  - Posterior spinal artery (PSA) aneurysms are a rare cause of subarachnoid 
      hemorrhage (SAH). The commonly abused street drug 
      3,4-methylenedioxymethamphetamine (MDMA) or 'Ecstasy' has been linked to both 
      systemic and neurological complications. A teenager presented with neck 
      stiffness, headaches and nausea after ingesting 'Ecstasy'. A brain CT was 
      negative for SAH but a CT angiogram suggested cerebral vasculitis. A lumbar 
      puncture showed SAH but a cerebral angiogram was negative. After a spinal MR 
      angiogram identified abnormalities on the dorsal surface of the cervical spinal 
      cord, a spinal angiogram demonstrated a left PSA 2 mm fusiform aneurysm. The 
      patient underwent surgery and the aneurysmal portion of the PSA was excised 
      without postoperative neurological sequelae. 'Ecstasy' can lead to neurovascular 
      inflammation, intracranial hemorrhage, SAH and potentially even de novo aneurysm 
      formation and subsequent rupture. PSA aneurysms may be treated by endovascular 
      proximal vessel occlusion or open surgical excision.
CI  - 2014 BMJ Publishing Group Ltd.
FAU - Johnson, Jeremiah
AU  - Johnson J
AD  - Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Patel, Shnehal
AU  - Patel S
AD  - Department of Neurology, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Saraf-Lavi, Efrat
AU  - Saraf-Lavi E
AD  - Department of Radiology, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Aziz-Sultan, Mohammad Ali
AU  - Aziz-Sultan MA
AD  - Department of Neurosurgery, Harvard Medical School/Brigham and Women's Hospital, 
      Boston, Massachusetts, USA.
FAU - Yavagal, Dileep R
AU  - Yavagal DR
AD  - Department of Neurology and Neurosurgery, University of Miami, Miami, Florida, 
      USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20140703
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 0 (Serotonin Agents)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Aneurysm, Ruptured/*chemically induced/diagnosis/surgery
MH  - Angiography
MH  - Cervical Vertebrae
MH  - Humans
MH  - Magnetic Resonance Angiography
MH  - Magnetic Resonance Imaging
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*poisoning
MH  - Serotonin Agents/*poisoning
MH  - Spinal Cord/*blood supply
MH  - Subarachnoid Hemorrhage/*chemically induced/diagnosis
MH  - Tomography, X-Ray Computed
MH  - *Vertebral Artery
PMC - PMC4091472
OTO - NOTNLM
OT  - Aneurysm
OT  - Drug
OT  - Inflammation
OT  - Spinal cord
OT  - Spine
EDAT- 2014/07/06 06:00
MHDA- 2015/01/22 06:00
PMCR- 2016/07/07
CRDT- 2014/07/05 06:00
PHST- 2014/07/05 06:00 [entrez]
PHST- 2014/07/06 06:00 [pubmed]
PHST- 2015/01/22 06:00 [medline]
PHST- 2016/07/07 00:00 [pmc-release]
AID - bcr-2014-011248 [pii]
AID - 10.1136/bcr-2014-011248 [doi]
PST - epublish
SO  - BMJ Case Rep. 2014 Jul 3;2014:bcr2014011248. doi: 10.1136/bcr-2014-011248.