PMID- 24997512
OWN - NLM
STAT- MEDLINE
DCOM- 20141010
LR  - 20140812
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1358
DP  - 2014 Sep 5
TI  - Salt-assisted dispersive liquid-liquid microextraction coupled with programmed 
      temperature vaporization gas chromatography-mass spectrometry for the 
      determination of haloacetonitriles in drinking water.
PG  - 14-9
LID - S0021-9673(14)00918-2 [pii]
LID - 10.1016/j.chroma.2014.06.021 [doi]
AB  - We report here a new analytical method for the simultaneous determination of 
      seven haloacetonitriles (HANs) in drinking water by coupling salt-assisted 
      dispersive liquid-liquid microextraction (SADLLME) with programmed temperature 
      vaporizer-gas chromatography-mass spectrometry (PTV-GC-MS). The newly developed 
      method involves the dispersion of the extractant in aqueous sample by addition of 
      a few grams of salt and no dispersion liquid was required as compared to the 
      traditional DLLME methods. The extractant (CH2Cl2, 50muL) and the salt (Na2SO4, 
      2.4g) were successively added to water (8mL) in a conical centrifuge tube that 
      was shaken for 1min and centrifuged (3500rpm, 3min). The aliquot of sedimented 
      phase (4muL) was then directly injected into the PTV-GC-MS system. The limits of 
      detection and quantification for the HANs were 0.4-13.2ngL(-1) and 
      1.2-43.9ngL(-1), respectively. The calibration curves showed good linearity 
      (r(2)>/=0.9904) over 3 orders of magnitude. The repeatability of the method was 
      investigated by evaluating the intra- and inter-day precisions. The relative 
      standard deviations (RSDs) obtained were lower than 10.2% and 7.8% at low and 
      high concentration levels. The relative recoveries ranged from 79.3% to 105.1%. 
      The developed methodology was applied for the analysis of seven HANs in several 
      drinking water samples in coastal and inland cities of China. It was demonstrated 
      to be a simple, sensible, reproducible and environment friendly method for the 
      determination of trace HANs in drinking water samples.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Ma, Huilian
AU  - Ma H
AD  - Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute 
      of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
FAU - Li, Yun
AU  - Li Y
AD  - Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute 
      of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
FAU - Zhang, Haijun
AU  - Zhang H
AD  - Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute 
      of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
FAU - Shah, Syed Mazhar
AU  - Shah SM
AD  - Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute 
      of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
FAU - Chen, Jiping
AU  - Chen J
AD  - Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute 
      of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. 
      Electronic address: chenjp@dicp.ac.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140612
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Acetonitriles)
RN  - 0 (Drinking Water)
RN  - 0 (Hydrocarbons, Halogenated)
RN  - 0 (Sulfates)
RN  - 0 (Water Pollutants, Chemical)
RN  - 0YPR65R21J (sodium sulfate)
SB  - IM
MH  - Acetonitriles/*analysis/chemistry
MH  - Calibration
MH  - Chemical Precipitation
MH  - Drinking Water/*analysis/chemistry
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Humans
MH  - Hydrocarbons, Halogenated/*analysis/chemistry
MH  - Hydrogen-Ion Concentration
MH  - Liquid Phase Microextraction/methods
MH  - Reproducibility of Results
MH  - Sulfates/*chemistry
MH  - Volatilization
MH  - Water Pollutants, Chemical/*analysis/chemistry
OTO - NOTNLM
OT  - Disinfection by-products
OT  - Dispersive liquid-liquid microextraction
OT  - Gas chromatography-mass spectrometry
OT  - Haloacetonitrile
OT  - Programmed temperature vaporizer
OT  - Salt-assisted
EDAT- 2014/07/07 06:00
MHDA- 2014/10/11 06:00
CRDT- 2014/07/07 06:00
PHST- 2013/12/17 00:00 [received]
PHST- 2014/06/06 00:00 [revised]
PHST- 2014/06/06 00:00 [accepted]
PHST- 2014/07/07 06:00 [entrez]
PHST- 2014/07/07 06:00 [pubmed]
PHST- 2014/10/11 06:00 [medline]
AID - S0021-9673(14)00918-2 [pii]
AID - 10.1016/j.chroma.2014.06.021 [doi]
PST - ppublish
SO  - J Chromatogr A. 2014 Sep 5;1358:14-9. doi: 10.1016/j.chroma.2014.06.021. Epub 
      2014 Jun 12.