PMID- 25000108 OWN - NLM STAT- MEDLINE DCOM- 20140925 LR - 20211021 IS - 1077-3525 (Print) IS - 2049-3967 (Electronic) IS - 1077-3525 (Linking) VI - 20 IP - 3 DP - 2014 Jul-Sep TI - Oxygen enrichment and its application to life support systems for workers in high-altitude areas. PG - 207-14 LID - 10.1179/2049396714Y.0000000068 [doi] AB - BACKGROUND: Workers coming from lowland regions are at risk of developing acute mountain sickness (AMS) when working in low oxygen high-altitude areas. OBJECTIVES: The aim of this study was to improve the conditions that lead to hypoxia and ensure the safety of the high-altitude workers. We analyzed the influence of low atmospheric pressure on the oxygen enrichment process in high-altitude areas using an engineering method called low-pressure swing adsorption (LPSA). METHODS: Fourteen male subjects were screened and divided into three groups by type of oxygen supply system used: (1) oxygen cylinder group; (2) LPSA oxygen dispersal group; and (3) control group. These tests included arterial oxygen saturation (SaO2), pulse rate (PR), breaths per minute (BPM), and blood pressure (BP). RESULTS: The results showed that after supplying oxygen using the LPSA method at the tunnel face, the SaO2 of workers increased; the incidence of acute mountain sickness, PR, and BPM significantly decreased. CONCLUSIONS: The LPSA life support system was found to be a simple, convenient, efficient, reliable, and applicable approach to ensure proper working conditions at construction sites in high-altitude areas. FAU - Li, Yongling AU - Li Y FAU - Liu, Yingshu AU - Liu Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Int J Occup Environ Health JT - International journal of occupational and environmental health JID - 9505217 RN - S88TT14065 (Oxygen) SB - IM MH - Adult MH - Altitude Sickness/etiology/*prevention & control MH - Blood Pressure MH - China MH - Heart Rate MH - Humans MH - Life Support Systems/*instrumentation MH - Male MH - *Occupational Health MH - Oxygen/*blood MH - Young Adult PMC - PMC4090886 OTO - NOTNLM OT - Acute mountain sickness OT - High altitude, OT - Hypoxia, OT - Life support system, OT - Low-pressure swing adsorption, OT - Oxygen supply, EDAT- 2014/07/08 06:00 MHDA- 2014/09/26 06:00 PMCR- 2015/07/01 CRDT- 2014/07/08 06:00 PHST- 2014/07/08 06:00 [entrez] PHST- 2014/07/08 06:00 [pubmed] PHST- 2014/09/26 06:00 [medline] PHST- 2015/07/01 00:00 [pmc-release] AID - 271 [pii] AID - 10.1179/2049396714Y.0000000068 [doi] PST - ppublish SO - Int J Occup Environ Health. 2014 Jul-Sep;20(3):207-14. doi: 10.1179/2049396714Y.0000000068.