PMID- 25001365
OWN - NLM
STAT- MEDLINE
DCOM- 20150330
LR  - 20221207
IS  - 1475-2840 (Electronic)
IS  - 1475-2840 (Linking)
VI  - 13
DP  - 2014 Jul 8
TI  - Neck circumference and early stage atherosclerosis: the cardiometabolic risk in 
      Chinese (CRC) study.
PG  - 107
LID - 10.1186/s12933-014-0107-x [doi]
AB  - BACKGROUND: Neck circumference (NC) has been previously related to 
      cardiometabolic risk factors. In this study we examined the association between 
      NC and early stage atherosclerosis in Chinese adults. METHODS: The study samples 
      were from a community-based health examination survey in central China. In total 
      2,318 men and women (18-64 y) were included in the final analyses. Carotid radial 
      pulse wave velocity (crPWV), carotid femoral PWV (cfPWV), carotid artery dorsalis 
      pedis PWV (cdPWV) and NC were measured. RESULTS: After adjustment for age, sex, 
      lipids, glucose, blood pressure, heart rate, body mass index (BMI), high NC was 
      significantly associated with an increasing trend of cfPWV, cdPWV and crPWV (P = 
      0.001, 0.049, and 0.038; respectively). In addition, we found significant 
      interaction between hypertension status and NC level in relation to cfPWV, 
      adjusted for age, sex, BMI, fasting glucose, lipids and heart rate(P for 
      interaction = 0.034). The associations between NC and cfPWV were significant 
      (P = 0.02) among those with hypertension, but not significant among those without 
      hypertension. CONCLUSIONS: Our data showed that high NC was associated with an 
      increased risk of early stage atherosclerosis in Chinese adults, independent of 
      other metabolic risk factors. Hypertension might modify the association between 
      NC and cfPWV.
FAU - Liang, Jun
AU  - Liang J
FAU - Wang, Yu
AU  - Wang Y
FAU - Li, Hongyan
AU  - Li H
FAU - Liu, Xuekui
AU  - Liu X
FAU - Qiu, Qinqin
AU  - Qiu Q
FAU - Qi, Lu
AU  - Qi L
LA  - eng
GR  - P30 DK046200/DK/NIDDK NIH HHS/United States
GR  - DK46200/DK/NIDDK NIH HHS/United States
GR  - HL071981/HL/NHLBI NIH HHS/United States
GR  - DK091718/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20140708
PL  - England
TA  - Cardiovasc Diabetol
JT  - Cardiovascular diabetology
JID - 101147637
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Asian People/ethnology
MH  - Atherosclerosis/*diagnosis/ethnology
MH  - Cardiovascular Diseases/*diagnosis/ethnology
MH  - Cross-Sectional Studies
MH  - Early Diagnosis
MH  - Female
MH  - Health Surveys/methods
MH  - Humans
MH  - Male
MH  - Metabolic Diseases/*diagnosis/ethnology
MH  - Middle Aged
MH  - Neck/*pathology
MH  - *Residence Characteristics
MH  - Risk Factors
MH  - Young Adult
PMC - PMC4100564
EDAT- 2014/07/09 06:00
MHDA- 2015/03/31 06:00
PMCR- 2014/07/08
CRDT- 2014/07/09 06:00
PHST- 2014/03/17 00:00 [received]
PHST- 2014/06/24 00:00 [accepted]
PHST- 2014/07/09 06:00 [entrez]
PHST- 2014/07/09 06:00 [pubmed]
PHST- 2015/03/31 06:00 [medline]
PHST- 2014/07/08 00:00 [pmc-release]
AID - s12933-014-0107-x [pii]
AID - 10.1186/s12933-014-0107-x [doi]
PST - epublish
SO  - Cardiovasc Diabetol. 2014 Jul 8;13:107. doi: 10.1186/s12933-014-0107-x.