PMID- 25006043
OWN - NLM
STAT- MEDLINE
DCOM- 20160401
LR  - 20150613
IS  - 1759-8486 (Electronic)
IS  - 1759-8478 (Linking)
VI  - 7
IP  - 7
DP  - 2015 Jul
TI  - Posterior spinal artery aneurysm rupture after 'Ecstasy' abuse.
PG  - e23
LID - 10.1136/neurintsurg-2014-011248.rep [doi]
AB  - Posterior spinal artery (PSA) aneurysms are a rare cause of subarachnoid 
      hemorrhage (SAH). The commonly abused street drug 
      3,4-methylenedioxymethamphetamine (MDMA) or 'Ecstasy' has been linked to both 
      systemic and neurological complications. A teenager presented with neck 
      stiffness, headaches and nausea after ingesting 'Ecstasy'. A brain CT was 
      negative for SAH but a CT angiogram suggested cerebral vasculitis. A lumbar 
      puncture showed SAH but a cerebral angiogram was negative. After a spinal MR 
      angiogram identified abnormalities on the dorsal surface of the cervical spinal 
      cord, a spinal angiogram demonstrated a left PSA 2 mm fusiform aneurysm. The 
      patient underwent surgery and the aneurysmal portion of the PSA was excised 
      without postoperative neurological sequelae. 'Ecstasy' can lead to neurovascular 
      inflammation, intracranial hemorrhage, SAH and potentially even de novo aneurysm 
      formation and subsequent rupture. PSA aneurysms may be treated by endovascular 
      proximal vessel occlusion or open surgical excision.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://group.bmj.com/group/rights-licensing/permissions.
FAU - Johnson, Jeremiah
AU  - Johnson J
AD  - Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Patel, Shnehal
AU  - Patel S
AD  - Department of Neurology, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Saraf-Lavi, Efrat
AU  - Saraf-Lavi E
AD  - Department of Radiology, University of Miami Miller School of Medicine, Miami, 
      Florida, USA.
FAU - Aziz-Sultan, Mohammad Ali
AU  - Aziz-Sultan MA
AD  - Department of Neurosurgery, Harvard Medical School/Brigham and Women's Hospital, 
      Boston, Massachusetts, USA.
FAU - Yavagal, Dileep R
AU  - Yavagal DR
AD  - Department of Neurology and Neurosurgery, University of Miami, Miami, Florida, 
      USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20140708
PL  - England
TA  - J Neurointerv Surg
JT  - Journal of neurointerventional surgery
JID - 101517079
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Aneurysm, Ruptured/*diagnosis/*etiology/surgery
MH  - Humans
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*adverse effects
MH  - Substance-Related Disorders/*complications/*diagnosis/surgery
MH  - Vertebral Artery/*pathology
OTO - NOTNLM
OT  - Aneurysm
OT  - Drug
OT  - Inflammation
OT  - Spinal cord
OT  - Spine
EDAT- 2014/07/10 06:00
MHDA- 2016/04/02 06:00
CRDT- 2014/07/10 06:00
PHST- 2014/05/02 00:00 [accepted]
PHST- 2014/07/10 06:00 [entrez]
PHST- 2014/07/10 06:00 [pubmed]
PHST- 2016/04/02 06:00 [medline]
AID - neurintsurg-2014-011248.rep [pii]
AID - 10.1136/neurintsurg-2014-011248.rep [doi]
PST - ppublish
SO  - J Neurointerv Surg. 2015 Jul;7(7):e23. doi: 10.1136/neurintsurg-2014-011248.rep. 
      Epub 2014 Jul 8.