PMID- 25006207 OWN - NLM STAT- MEDLINE DCOM- 20150423 LR - 20140815 IS - 1460-2350 (Electronic) IS - 0268-1161 (Linking) VI - 29 IP - 9 DP - 2014 Sep TI - Preimplantation genetic screening: back to the future. PG - 1846-50 LID - 10.1093/humrep/deu163 [doi] AB - All agree that in hindsight the rapid adoption of preimplantation genetic screening (PGS) using cleavage stage biopsy and fluorescence in situ hybridization (FISH) in routine clinical practice without proper evaluation of (cost-)effectiveness basically resulted in couples paying more money for a less effective treatment. Now, almost 20 years later, we are on the verge of a new era of PGS. But have things really changed or are we simply going back to the future? CI - (c) The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com. FAU - Mastenbroek, Sebastiaan AU - Mastenbroek S AD - Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Q3-119, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands s.mastenbroek@amc.uva.nl. FAU - Repping, Sjoerd AU - Repping S AD - Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Q3-119, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. LA - eng PT - Journal Article DEP - 20140708 PL - England TA - Hum Reprod JT - Human reproduction (Oxford, England) JID - 8701199 SB - IM MH - Embryonic Development MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Pregnancy MH - Pregnancy Rate MH - Preimplantation Diagnosis/*methods/standards/trends MH - Reproductive Techniques, Assisted/standards/trends OTO - NOTNLM OT - IVF/ICSI OT - PGS OT - aneuploidy OT - efficacy OT - randomized controlled trials EDAT- 2014/07/10 06:00 MHDA- 2015/04/24 06:00 CRDT- 2014/07/10 06:00 PHST- 2014/07/10 06:00 [entrez] PHST- 2014/07/10 06:00 [pubmed] PHST- 2015/04/24 06:00 [medline] AID - deu163 [pii] AID - 10.1093/humrep/deu163 [doi] PST - ppublish SO - Hum Reprod. 2014 Sep;29(9):1846-50. doi: 10.1093/humrep/deu163. Epub 2014 Jul 8.