PMID- 2500687 OWN - NLM STAT- MEDLINE DCOM- 19890802 LR - 20180216 IS - 0025-7931 (Print) IS - 0025-7931 (Linking) VI - 55 IP - 1 DP - 1989 TI - Resting gas exchange in nonsmoking bituminous-coal miners with simple pneumoconiosis. PG - 28-32 AB - Gas exchange at rest under normoxic conditions was studied in 2,297 nonsmoking bituminous-coal miners with and without simple coal workers' pneumoconiosis (CWP). Measurements of arterial oxygen tension (Pao2) and arterial carbon dioxide tension (Paco2) from blood gas samples obtained at rest in the seated position were used to calculate the alveolar-arterial oxygen tension difference, (A-a)Do2, using the classic alveolar-air equation. We then recalculated the (A-a)Do2 using the age-predicted Pao2 for each miner. The difference between the actual and the predicted (A-a)Do2 was measured and the mean difference for each category of simple CWP was analyzed. We found no evidence that the resting gas exchange differs significantly from the age-predicted (A-a)Do2 in the nonsmoking bituminous-coal minor with simple CWP. Likewise, there is no significant change in (A-a)Do2 with change in the category of simple CWP. FAU - Roy, T M AU - Roy TM AD - Division of Respiratory and Environmental Medicine, University of Louisville School of Medicine, Ky. FAU - Walker, J F AU - Walker JF FAU - Snider, H L AU - Snider HL FAU - Anderson, W H AU - Anderson WH LA - eng PT - Journal Article PL - Switzerland TA - Respiration JT - Respiration; international review of thoracic diseases JID - 0137356 RN - 142M471B3J (Carbon Dioxide) RN - S88TT14065 (Oxygen) SB - IM MH - Age Factors MH - Carbon Dioxide/blood MH - *Coal Mining MH - Humans MH - Middle Aged MH - Oxygen/blood MH - Pneumoconiosis/blood/*physiopathology MH - *Pulmonary Gas Exchange MH - Smoking MH - Ventilation-Perfusion Ratio EDAT- 1989/01/01 00:00 MHDA- 1989/01/01 00:01 CRDT- 1989/01/01 00:00 PHST- 1989/01/01 00:00 [pubmed] PHST- 1989/01/01 00:01 [medline] PHST- 1989/01/01 00:00 [entrez] AID - 10.1159/000195702 [doi] PST - ppublish SO - Respiration. 1989;55(1):28-32. doi: 10.1159/000195702.