PMID- 25009817
OWN - NLM
STAT- MEDLINE
DCOM- 20150212
LR  - 20211021
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2014
DP  - 2014
TI  - Microincision vitrectomy surgery in vitreomacular traction syndrome of retinitis 
      pigmentosa patients.
PG  - 537081
LID - 10.1155/2014/537081 [doi]
LID - 537081
AB  - PURPOSE: To investigate long-term retinal changes after microincision pars plana 
      vitrectomy surgery (MIVS) and internal limiting membrane (ILM) peeling outcome in 
      retinitis pigmentosa (RP) patients affected by vitreomacular traction syndrome 
      (VMT) with higher vitreous surface adhesion or coexisting epiretinal membrane 
      (ERM). METHODS: Eight RP patients suffering from VMT were evaluated by means of 
      best corrected visual acuity (BCVA), anterior and posterior binocular 
      examination, spectral-domain optical coherence tomography (SD-OCT), MP-1 
      microperimetry (MP-1), and full-field electroretinogram (ERG), before MIVS and 
      ILM peeling and during the 36-month follow-up. Patients were hospitalized for two 
      days after the surgery. Surgical procedure was performed following this schedule: 
      surgical removal of crystalline lens (MICS), MIVS with 23-gauge sutureless system 
      trocars, core vitreous body removal, and balanced-sterile-salin-solution- (BSS-) 
      air-gas (SF6) exchange. RESULTS: All patients presented visual acuity (VA) 
      increase after MIVS. None of the patients developed ocular hypertension or 
      vitreomacular adhesions during the 3-year follow-up. MP-1 bivariate contour 
      ellipse area (BCEA) was reduced in its dimensions and improved in all patients 
      demonstrating a better fixation. CONCLUSIONS: MIVS could be the gold standard 
      therapy in RP patients with VMT and higher vitreous surface adhesion or 
      coexisting ERM if medical therapy is not applicable or not effective.
FAU - Vingolo, Enzo Maria
AU  - Vingolo EM
AD  - Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 
      04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 
      Rome, Italy.
FAU - Gerace, Emanuele
AU  - Gerace E
AD  - Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 
      04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 
      Rome, Italy.
FAU - Valente, Stefano
AU  - Valente S
AD  - Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 
      04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 
      Rome, Italy.
FAU - Spadea, Leopoldo
AU  - Spadea L
AD  - Department of Ophthalmology, Polo Pontino, A. Fiorini Hospital, Via Firenze, 
      04019 Terracina, Italy ; Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 
      Rome, Italy.
FAU - Nebbioso, Marcella
AU  - Nebbioso M
AD  - Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy ; Department 
      of Sense Organs, Centre of Ocular Electrophysiology, Sapienza University of Rome, 
      Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20140609
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Recovery of Function
MH  - *Retinitis Pigmentosa/pathology/physiopathology/surgery
MH  - Syndrome
MH  - *Vitrectomy
MH  - *Vitreous Body/pathology/physiopathology
PMC - PMC4070290
EDAT- 2014/07/11 06:00
MHDA- 2015/02/13 06:00
PMCR- 2014/06/09
CRDT- 2014/07/11 06:00
PHST- 2014/02/24 00:00 [received]
PHST- 2014/04/22 00:00 [revised]
PHST- 2014/05/22 00:00 [accepted]
PHST- 2014/07/11 06:00 [entrez]
PHST- 2014/07/11 06:00 [pubmed]
PHST- 2015/02/13 06:00 [medline]
PHST- 2014/06/09 00:00 [pmc-release]
AID - 10.1155/2014/537081 [doi]
PST - ppublish
SO  - Biomed Res Int. 2014;2014:537081. doi: 10.1155/2014/537081. Epub 2014 Jun 9.