PMID- 25010282
OWN - NLM
STAT- MEDLINE
DCOM- 20140915
LR  - 20140715
IS  - 1096-0341 (Electronic)
IS  - 0042-6822 (Linking)
VI  - 460-461
DP  - 2014 Jul
TI  - Genomic organization and molecular characterization of porcine cytomegalovirus.
PG  - 165-72
LID - S0042-6822(14)00228-1 [pii]
LID - 10.1016/j.virol.2014.05.014 [doi]
AB  - A strain of the porcine cytomegalovirus (PCMV), which causes inclusion body 
      rhinitis in newborn piglets, has been characterized with respect to its complete 
      genome sequence. The virus genome is 128,367bp, containing 79 predicted open 
      reading frames (ORFs). Of these ORFs, 69 have counterparts in human herpesvirus 
      6A (HHV-6A), 6B (HHV-6B) and 7 (HHV-7), and two ORFs are homologous to other 
      members in the subfamily Betaherpesvirinae. Eight ORFs have no homologs in 
      herpesvirus. Homologs had higher identity and possessed similar orientation and 
      location as roseoloviruses. The PCMV genome is a DR-U-DR type, similar to HHV-6A, 
      HHV-6B and HHV-7, but the PCMV DR is shorter and lacks predicted genes and 
      telomere-like sequences. Phylogenetic analyses of several core genes indicate 
      that PCMV could be clustered in a branch with roseoloviruses. We suggest that 
      PCMV could be classified as a member of the genus Roseolovirus of the subfamily 
      Betaherpesvirinae.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Gu, Weiwei
AU  - Gu W
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China.
FAU - Zeng, Nanfang
AU  - Zeng N
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China.
FAU - Zhou, Lei
AU  - Zhou L
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China.
FAU - Ge, Xinna
AU  - Ge X
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China.
FAU - Guo, Xin
AU  - Guo X
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China.
FAU - Yang, Hanchun
AU  - Yang H
AD  - Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, 
      College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, 
      China Agricultural University, Beijing, People's Republic of China. Electronic 
      address: yanghanchun1@cau.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140604
PL  - United States
TA  - Virology
JT  - Virology
JID - 0110674
RN  - 0 (Viral Proteins)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Cytomegalovirus/classification/*genetics/isolation & purification
MH  - Cytomegalovirus Infections/*veterinary/virology
MH  - *Genome, Viral
MH  - Genomics
MH  - Humans
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - Swine
MH  - Swine Diseases/*virology
MH  - Viral Proteins/genetics
OTO - NOTNLM
OT  - Comparative analysis
OT  - Genome
OT  - Organization and characterization
OT  - Porcine cytomegalovirus (PCMV)
OT  - Sequencing
EDAT- 2014/07/11 06:00
MHDA- 2014/09/16 06:00
CRDT- 2014/07/11 06:00
PHST- 2013/10/07 00:00 [received]
PHST- 2013/10/17 00:00 [revised]
PHST- 2014/05/07 00:00 [accepted]
PHST- 2014/07/11 06:00 [entrez]
PHST- 2014/07/11 06:00 [pubmed]
PHST- 2014/09/16 06:00 [medline]
AID - S0042-6822(14)00228-1 [pii]
AID - 10.1016/j.virol.2014.05.014 [doi]
PST - ppublish
SO  - Virology. 2014 Jul;460-461:165-72. doi: 10.1016/j.virol.2014.05.014. Epub 2014 
      Jun 4.