PMID- 25013571
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20140711
LR  - 20211021
IS  - 2008-6482 (Print)
IS  - 2008-6490 (Electronic)
IS  - 2008-6482 (Linking)
VI  - 1
IP  - 2
DP  - 2010
TI  - The impact of hepatitis B infection on outcome of kidney transplantation: a 
      long-term study.
PG  - 91-3
AB  - BACKGROUND: With the success of kidney transplantation, liver disease has emerged 
      as an important cause of morbidity and mortality in kidney recipients. OBJECTIVE: 
      To determine the impact of hepatitis B virus (HBV) infection on patients and 
      graft survival in both short- and long-terms. METHODS: 99 renal transplant 
      patients infected with HBV on follow-up in two major transplant centers were 
      included in a retrospective study. These patients were grafted between 1986 and 
      2005 and divided into two groups: (1) those only positive for hepatitis B surface 
      antigen (HBsAg) and (2) those who were also positive for hepatitis C virus 
      antibodies (HCV Ab). RESULTS: There were 88 patients with HBsAg(+) and 11 with 
      both HBsAg(+) and HCV Ab(+). The mean+/-SD age of patients was 38.8+/-13.2 years, and 
      the median follow-up after transplantation was 19 months. Although not 
      significant, the allograft survival rate in the first group (HBV(+)) was better 
      compared to that in the second group (HBV(+) and HCV(+)); 1, 5 and 10 years graft 
      survival rates were 91, 77 and 62 in the first group and 70, 56 and 28 in the 
      second group, respectively (P=0.07). The overall mortality was 5% (4 of 88) in 
      the first and 27% (3 of 11) in the second group (P=0.02). CONCLUSION: Renal 
      allograft recipients with HBV and HCV infections has a poor survival rate 
      compared to patients with only HBV infection. However, there is no significant 
      difference in terms of renal graft survival between the two groups.
FAU - Einollahi, B
AU  - Einollahi B
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Alavian, S M
AU  - Alavian SM
AD  - Baqiyatallah Research Center for Gastroenterology and Liver Disease, Baqiyatallah 
      University of Medical Sciences, Tehran, IR Iran.
FAU - Lessan-Pezeshki, M
AU  - Lessan-Pezeshki M
AD  - Department of Nephrology, Tehran University of Medical Sciences, Tehran, IR Iran.
FAU - Simforoosh, N
AU  - Simforoosh N
AD  - Renal Transplantation Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, IR Iran.
FAU - Nourbala, M H
AU  - Nourbala MH
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Rostami, Z
AU  - Rostami Z
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Pourfarziani, V
AU  - Pourfarziani V
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Nemati, E
AU  - Nemati E
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Sharafi, M
AU  - Sharafi M
AD  - Nephrology and Urology Research Center, Baqiyatallah University of Medical 
      Sciences, Tehran, IR Iran.
FAU - Nafar, M
AU  - Nafar M
AD  - Renal Transplantation Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, IR Iran.
FAU - Pour-Reza Gholi, F
AU  - Pour-Reza Gholi F
AD  - Renal Transplantation Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, IR Iran.
FAU - Firoozan, A
AU  - Firoozan A
AD  - Renal Transplantation Center, Shahid Beheshti University of Medical Sciences, 
      Tehran, IR Iran.
LA  - eng
PT  - Journal Article
PL  - Iran
TA  - Int J Organ Transplant Med
JT  - International journal of organ transplantation medicine
JID - 101535773
PMC - PMC4089227
OTO - NOTNLM
OT  - Hepatitis B virus
OT  - Hepatitis C virus
OT  - Kidney transplantation
EDAT- 2010/01/01 00:00
MHDA- 2010/01/01 00:01
PMCR- 2010/01/01
CRDT- 2014/07/12 06:00
PHST- 2014/07/12 06:00 [entrez]
PHST- 2010/01/01 00:00 [pubmed]
PHST- 2010/01/01 00:01 [medline]
PHST- 2010/01/01 00:00 [pmc-release]
AID - ijotm-1-091 [pii]
PST - ppublish
SO  - Int J Organ Transplant Med. 2010;1(2):91-3.