PMID- 25013723
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20151026
LR  - 20220318
IS  - 1828-695X (Print)
IS  - 2049-6958 (Electronic)
IS  - 1828-695X (Linking)
VI  - 9
IP  - 1
DP  - 2014
TI  - Association between peripheral muscle strength, exercise performance, and 
      physical activity in daily life in patients with Chronic Obstructive Pulmonary 
      Disease.
PG  - 37
LID - 10.1186/2049-6958-9-37 [doi]
AB  - BACKGROUND: Resistance training of peripheral muscles has been recommended in 
      order to increase muscle strength in patients with Chronic Obstructive Pulmonary 
      Disease (COPD). However, whether peripheral muscle strength is associated with 
      exercise performance (EP) and physical activity in daily life (PADL) in these 
      patients needs to be investigated. The aim of this study is to evaluate whether 
      strength of the quadriceps muscle (QS) is associated with EP and daily PADL in 
      patients with COPD. METHODS: We studied patients with COPD (GOLD A-D) and 
      measured maximal isometric strength of the left QS. PADL was measured for 7 days 
      with a SenseWear-Pro(R) accelerometer. EP was quantified by the 6-minute walk 
      distance (6MWD), the number of stands in the Sit-to-Stand Test (STST), and the 
      handgrip-strength. Univariate and multivariate analyses were used to examine 
      possible associations between QS, PADL and EP. RESULTS: In 27 patients with COPD 
      with a mean (SD) FEV1 of 37.6 (17.6)% predicted, QS was associated with 6MWD, 
      STST, and handgrip-strength but not with PADL. Multiple linear regression 
      analyses showed that QS was independently associated with the 6MWD (beta = 0.42, 95% 
      CI 0.09 to 0.84, p = 0.019), STST (beta = 0.50, 95% CI 0.11 to 0.86, p = 0.014) and 
      with handgrip-strength (beta = 0.45, 95% CI 0.05 to 0.84, p = 0.038). CONCLUSIONS: 
      Peripheral muscle strength may be associated with exercise performance but not 
      with physical activity in daily life. This may be due to the fact that EP tests 
      evaluate patients' true abilities while PADL accelerometers may not.
FAU - Rausch-Osthoff, Anne-Kathrin
AU  - Rausch-Osthoff AK
AD  - Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland ; 
      Department of Physiotherapy, Zurich University of Applied Sciences, Winterthur, 
      Switzerland ; Zurich University of Applied Sciences, School of Health 
      Professions, Department of Physiotherapy, Technikumstrasse 71, 8401 Winterthur, 
      Switzerland.
FAU - Kohler, Malcolm
AU  - Kohler M
AD  - Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland ; Centre 
      for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.
FAU - Sievi, Noriane A
AU  - Sievi NA
AD  - Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland.
FAU - Clarenbach, Christian F
AU  - Clarenbach CF
AD  - Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland.
FAU - van Gestel, Arnoldus Jr
AU  - van Gestel AJ
AD  - Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland ; 
      Department of Physiotherapy, Zurich University of Applied Sciences, Winterthur, 
      Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20140703
PL  - Italy
TA  - Multidiscip Respir Med
JT  - Multidisciplinary respiratory medicine
JID - 101477642
PMC - PMC4091091
OTO - NOTNLM
OT  - Accelerometer
OT  - Handgrip-strength
OT  - Quadriceps strength
OT  - Sit-to-stand-test
OT  - Six-minute-walk-distance
EDAT- 2014/07/12 06:00
MHDA- 2014/07/12 06:01
PMCR- 2014/07/03
CRDT- 2014/07/12 06:00
PHST- 2014/02/11 00:00 [received]
PHST- 2014/06/18 00:00 [accepted]
PHST- 2014/07/12 06:00 [entrez]
PHST- 2014/07/12 06:00 [pubmed]
PHST- 2014/07/12 06:01 [medline]
PHST- 2014/07/03 00:00 [pmc-release]
AID - 2049-6958-9-37 [pii]
AID - 10.1186/2049-6958-9-37 [doi]
PST - epublish
SO  - Multidiscip Respir Med. 2014 Jul 3;9(1):37. doi: 10.1186/2049-6958-9-37. 
      eCollection 2014.