PMID- 25014661
OWN - NLM
STAT- MEDLINE
DCOM- 20150622
LR  - 20181202
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 118
DP  - 2015 Jan
TI  - Method development for the simultaneous determination of polybrominated, 
      polychlorinated, mixed polybrominated/chlorinated dibenzo-p-dioxins and 
      dibenzofurans, polychlorinated biphenyls and polybrominated diphenyl ethers in 
      fish.
PG  - 72-80
LID - S0045-6535(14)00768-1 [pii]
LID - 10.1016/j.chemosphere.2014.06.032 [doi]
AB  - An analytical methodology was developed for simultaneous determination of five 
      groups of persistent organic pollutants (POPs) including polybrominated, 
      polychlorinated and mixed brominated-chlorinated dibenzo-p-dioxins and 
      dibenzofurans (PBDD/DFs, PCDD/DFs and PXDD/DFs, respectively), polychlorinated 
      biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in fish samples. The 
      presented analytical approach was based on well established and robust method for 
      determination of PCDD/DFs and PCBs, which was augmented with gas chromatography 
      coupled to high resolution mass spectrometry (GC-HRMS) to include PBDEs, as well 
      as poorly investigated PBDD/DFs and PXDD/DFs at toxicologically significant 
      levels. Intensive clean-up and fractionation procedures in combination with 
      optimized instrumental parameters provided reliable detection and quantification 
      of these compounds. The application of (13)C12-labeled surrogates of analyzed 
      compounds allowed the internal standardization and accurate measurement of 
      selected contaminants. The developed procedure was validated while taking into 
      account the Commission Regulation (EU) 252/2012 requirements for PCDD/DFs and 
      PCBs, and was used to measure the occurrence of priority POPs in Baltic wild 
      salmon.
CI  - Copyright (c) 2014 Elsevier Ltd. All rights reserved.
FAU - Zacs, D
AU  - Zacs D
AD  - Institute of Food Safety, Animal Health and Environment "BIOR", Lejupes iela 3, 
      Riga LV-1076, Latvia; University of Latvia, Department of Chemistry, Kr. 
      Valdemara iela 48, Riga LV-1013, Latvia. Electronic address: 
      dzintars.zachs@gmail.com.
FAU - Rjabova, J
AU  - Rjabova J
AD  - Institute of Food Safety, Animal Health and Environment "BIOR", Lejupes iela 3, 
      Riga LV-1076, Latvia.
FAU - Viksna, A
AU  - Viksna A
AD  - University of Latvia, Department of Chemistry, Kr. Valdemara iela 48, Riga 
      LV-1013, Latvia.
FAU - Bartkevics, V
AU  - Bartkevics V
AD  - Institute of Food Safety, Animal Health and Environment "BIOR", Lejupes iela 3, 
      Riga LV-1076, Latvia; University of Latvia, Department of Chemistry, Kr. 
      Valdemara iela 48, Riga LV-1013, Latvia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140709
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Benzofurans)
RN  - 0 (Dioxins)
RN  - 0 (Halogenated Diphenyl Ethers)
RN  - 0 (Water Pollutants, Chemical)
RN  - 7REL09ZX35 (pentabromodiphenyl ether)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Animals
MH  - Benzofurans/metabolism
MH  - Chromatography, Gel
MH  - Dioxins/metabolism
MH  - Environmental Monitoring/*methods
MH  - Female
MH  - Gas Chromatography-Mass Spectrometry
MH  - Halogenated Diphenyl Ethers/metabolism
MH  - Latvia
MH  - Male
MH  - Polychlorinated Biphenyls/metabolism
MH  - Salmo salar/*metabolism
MH  - Water Pollutants, Chemical/*metabolism
OTO - NOTNLM
OT  - Fish
OT  - GC-HRMS
OT  - PBDD/DFs
OT  - POPs
OT  - PXDD/DFs
OT  - Simultaneous determination
EDAT- 2014/07/12 06:00
MHDA- 2015/06/24 06:00
CRDT- 2014/07/12 06:00
PHST- 2013/06/02 00:00 [received]
PHST- 2014/05/20 00:00 [revised]
PHST- 2014/06/15 00:00 [accepted]
PHST- 2014/07/12 06:00 [entrez]
PHST- 2014/07/12 06:00 [pubmed]
PHST- 2015/06/24 06:00 [medline]
AID - S0045-6535(14)00768-1 [pii]
AID - 10.1016/j.chemosphere.2014.06.032 [doi]
PST - ppublish
SO  - Chemosphere. 2015 Jan;118:72-80. doi: 10.1016/j.chemosphere.2014.06.032. Epub 
      2014 Jul 9.