PMID- 25015351
OWN - NLM
STAT- MEDLINE
DCOM- 20140926
LR  - 20220311
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Linking)
VI  - 55
IP  - 7
DP  - 2014 Jul 11
TI  - The detection of macular analysis by SD-OCT for optic chiasmal compression 
      neuropathy and nasotemporal overlap.
PG  - 4667-72
LID - 10.1167/iovs.14-14766 [doi]
AB  - PURPOSE: To assess the diagnostic performance of the macular parameters detected 
      by spectral-domain optical coherence tomography (SD-OCT) in band atrophy (BA) 
      eyes. METHODS: Forty-nine BA eyes with permanent temporal hemianopia and 89 
      normal eyes were enrolled. Any patients who had nasal visual field loss were 
      excluded. Each participant was imaged by three-dimensional (3D) OCT-2000, and 10 
      x 10 grids in the macula were automatically allocated. The thickness of the 
      macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL)+ (GCL+inner 
      plexiform layer [IPL]), and GCL++ (RNFL+GCL+IPL) in both nasal and temporal 
      hemiretina was calculated and compared between the BA and normal eyes. The areas 
      under the receiver operating characteristic curves (AUCs) in these parameters 
      were compared between the nasal hemiretina and the temporal hemiretina. RESULTS: 
      All the parameters in the BA eyes were significantly thinner than those in the 
      normal eyes. The AUCs for the mRNFL, GCL+, and GCL++ thickness in the nasal 
      hemiretina were 0.890, 0.988, and 0.981, respectively. The parameters in the 
      nasal hemiretina showed significantly higher AUCs than those parameters in the 
      temporal hemiretina. In the temporal hemiretina, the damaged grids in the mRNFL 
      were located in the arcuate areas in each hemifield. CONCLUSIONS: The inner 
      macular parameters in the nasal hemiretina exhibited high diagnostic abilities to 
      detect BA. The GCL+ was more affected than mRNFL. The characteristic pattern of 
      mRNFL and GCL+ thinning was implicated in the anatomical architecture regarding 
      the nasotemporal overlap of the crossed and uncrossed fibers around the fovea. 
      (www.umin.ac.jp/ctr number, UMIN000006900.).
CI  - Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.
FAU - Akashi, Azusa
AU  - Akashi A
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Kanamori, Akiyasu
AU  - Kanamori A
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Ueda, Kaori
AU  - Ueda K
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Matsumoto, Yoshiko
AU  - Matsumoto Y
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Yamada, Yuko
AU  - Yamada Y
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
FAU - Nakamura, Makoto
AU  - Nakamura M
AD  - Division of Ophthalmology, Department of Surgery, Kobe University Graduate School 
      of Medicine, Kobe, Japan.
LA  - eng
SI  - JPRN/UMIN000006900
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140711
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - Adenoma/pathology
MH  - Adult
MH  - Aged
MH  - Area Under Curve
MH  - Central Nervous System Cysts/*pathology
MH  - Craniopharyngioma/pathology
MH  - Diagnostic Techniques, Ophthalmological
MH  - Female
MH  - Hemianopsia/diagnosis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nerve Compression Syndromes/*diagnosis
MH  - Nerve Fibers/*pathology
MH  - Optic Chiasm/*pathology
MH  - Pituitary Neoplasms/*pathology
MH  - ROC Curve
MH  - Retinal Diseases/diagnosis
MH  - Retinal Ganglion Cells/*pathology
MH  - *Tomography, Optical Coherence
OTO - NOTNLM
OT  - band atrophy
OT  - chiasmal compression
OT  - ganglion cell layer
OT  - optical coherence tomography
OT  - retinal nerve fiber layer
EDAT- 2014/07/13 06:00
MHDA- 2014/09/27 06:00
CRDT- 2014/07/13 06:00
PHST- 2014/07/13 06:00 [entrez]
PHST- 2014/07/13 06:00 [pubmed]
PHST- 2014/09/27 06:00 [medline]
AID - iovs.14-14766 [pii]
AID - 10.1167/iovs.14-14766 [doi]
PST - epublish
SO  - Invest Ophthalmol Vis Sci. 2014 Jul 11;55(7):4667-72. doi: 10.1167/iovs.14-14766.