PMID- 25017624
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20161230
IS  - 1989-4600 (Electronic)
IS  - 1888-9891 (Linking)
VI  - 8
IP  - 2
DP  - 2015 Apr-Jun
TI  - Efficacy of a family intervention program for prevention of hospitalization in 
      patients with schizophrenia. A naturalistic multicenter controlled and randomized 
      study in Spain.
PG  - 83-91
LID - S1888-9891(13)00124-9 [pii]
LID - 10.1016/j.rpsm.2013.11.001 [doi]
AB  - BACKGROUND: According to most relevant guidelines, family psycho-educational 
      interventions are considered to be one the most effective psychosocial treatments 
      for people with schizophrenia. The main outcome measure in controlled and 
      randomized studies has been prevention of relapses and admissions, and 
      encouragement of compliance, although some questions remain about its 
      applicability and results in clinical practice. OBJECTIVES: The aim of study was 
      to evaluate the efficacy and implementation of a single family psychoeducational 
      intervention in 'real' conditions for people diagnosed with schizophrenia. 
      METHODS: A total of 88 families were randomized in two groups. The family 
      intervention group received a 12 months psychoeducational treatment, and the 
      other group followed normal standard treatment. Assessments were made at 
      baseline, at 12 and at 18 months. The main outcome measure was hospitalization, 
      and secondary outcome measures were clinical condition (BPRS-E) and social 
      disability (DAS-II). RESULTS: A total of 71 patients finished the study (34 
      family intervention group and 37 control group). Patients who received family 
      intervention reduced the risk of hospitalization by 40% (P = .4018; 95%CI: 
      0.1833-0.6204). Symptomatology improved significantly at 12 months (P = .4018; 
      95%CI: 0.1833-0.6204), but not at 18 months (P = .4018; 95%CI: 0.1833-0.6204). 
      Social disability was significantly reduced in the family intervention group at 
      12 months and 18 months. CONCLUSIONS: Family psychoeducational intervention 
      reduces hospitalization risk and improves clinical condition and social 
      functioning of people with schizophrenia.
CI  - Copyright (c) 2013 SEP y SEPB. Published by Elsevier Espana. All rights reserved.
FAU - Mayoral, Fermin
AU  - Mayoral F
AD  - Unidad de Gestion Clinica de Salud Mental, Instituto de Biomedicina de Malaga 
      (IBIMA), Hospital Regional Universitario de Malaga, Malaga, Espana. Electronic 
      address: fermin.mayoral.sspa@juntadeandalucia.es.
FAU - Berrozpe, Adela
AU  - Berrozpe A
AD  - Serveis de Salut Mental, Parc Sanitari Sant Joan de Deu, El Prat de Llobregat, 
      Barcelona, Espana.
FAU - de la Higuera, Jesus
AU  - de la Higuera J
AD  - Unidad de Gestion Clinica de Salud Mental, Hospital Universitario de Puerto Real, 
      Cadiz, Espana.
FAU - Martinez-Jambrina, Juan Jose
AU  - Martinez-Jambrina JJ
AD  - AGC Salud Mental, Area Sanitaria 3, Aviles, Asturias, Espana.
FAU - de Dios Luna, Juan
AU  - de Dios Luna J
AD  - Departamento de Bioestadistica, Universidad de Granada, Granada, Espana.
FAU - Torres-Gonzalez, Francisco
AU  - Torres-Gonzalez F
AD  - Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Red 
      Maristan, Universidad de Granada, Granada, Espana.
LA  - eng
LA  - spa
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20140710
PL  - Spain
TA  - Rev Psiquiatr Salud Ment
JT  - Revista de psiquiatria y salud mental
JID - 101528851
SB  - IM
MH  - Adult
MH  - *Caregivers
MH  - *Family
MH  - Female
MH  - Health Education/*methods
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Professional-Family Relations
MH  - Schizophrenia/*therapy
MH  - Spain
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Esquizofrenia
OT  - Family intervention
OT  - Intervencion familiar
OT  - Psychosocial treatments
OT  - Schizophrenia
OT  - Tratamientos psicosociales
EDAT- 2014/07/16 06:00
MHDA- 2016/12/15 06:00
CRDT- 2014/07/15 06:00
PHST- 2013/07/23 00:00 [received]
PHST- 2013/10/30 00:00 [revised]
PHST- 2013/11/15 00:00 [accepted]
PHST- 2014/07/15 06:00 [entrez]
PHST- 2014/07/16 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - S1888-9891(13)00124-9 [pii]
AID - 10.1016/j.rpsm.2013.11.001 [doi]
PST - ppublish
SO  - Rev Psiquiatr Salud Ment. 2015 Apr-Jun;8(2):83-91. doi: 
      10.1016/j.rpsm.2013.11.001. Epub 2014 Jul 10.