PMID- 25020263
OWN - NLM
STAT- MEDLINE
DCOM- 20150611
LR  - 20141007
IS  - 1873-2933 (Electronic)
IS  - 0009-9120 (Linking)
VI  - 47
IP  - 15
DP  - 2014 Oct
TI  - Quality assurance in the laboratory testing process: indirect estimation of the 
      reference intervals for platelet parameters in neonates.
PG  - 33-7
LID - S0009-9120(14)00494-9 [pii]
LID - 10.1016/j.clinbiochem.2014.07.002 [doi]
AB  - OBJECTIVES: One of the most powerful tools that laboratory medicine uses to help 
      the clinical decision-making process is the reference interval (RI). By 
      establishing their own RIs in accordance with the analytical method they apply, 
      the laboratories contribute to the quality assurance in the laboratory testing 
      process. DESIGN AND METHODS: This study estimates the RIs of the platelet 
      parameters in neonates for Nihon Celltac F hematology automatic analyzer. A 
      database of 1058 venous complete blood counts in neonates in their first day of 
      life has been processed through two different statistical methods: the simple 
      non-parametric method and the bootstrap method. RESULTS: The results give the 
      mean+/-SE(RI) for: platelet count (PLT)=270.39+/-0.68 (156-387x10(9)/L); plateletcrit 
      (PCT)=0.151+/-0.0072 (0.10-0.23%); mean platelet volume (MPV)=5.72+/-0.0085 
      (4.0-8.0fL): platelet distribution width (PDW)=17.67+/-3.03 (16.3-18.9%). 
      CONCLUSIONS: These values are in agreement with the RI for platelet count 
      reported in literature, but the estimated RIs of the platelet indices are 
      different. This justifies the need for laboratories to determine their own RIs.
CI  - Copyright (c) 2014 The Canadian Society of Clinical Chemists. Published by Elsevier 
      Inc. All rights reserved.
FAU - Grecu, Daniela Stefania
AU  - Grecu DS
AD  - University of Medicine and Pharmacy "Victor Babes" Timisoara, Biochemistry and 
      Pharmacology Department, 2, Eftimie Murgu Square, 300041 Timisoara, Romania.
FAU - Paulescu, Eugenia
AU  - Paulescu E
AD  - West University of Timisoara, Physics Department, V Parvan 4, 300223 Timisoara, 
      Romania. Electronic address: eugeniat@physics.uvt.ro.
LA  - eng
PT  - Journal Article
DEP - 20140712
PL  - United States
TA  - Clin Biochem
JT  - Clinical biochemistry
JID - 0133660
SB  - IM
MH  - Blood Platelets/*metabolism
MH  - Humans
MH  - Infant, Newborn
MH  - *Platelet Count
MH  - *Quality Assurance, Health Care
MH  - Reference Values
MH  - Regression Analysis
OTO - NOTNLM
OT  - Neonates
OT  - Platelet parameters
OT  - References intervals
EDAT- 2014/07/16 06:00
MHDA- 2015/06/13 06:00
CRDT- 2014/07/15 06:00
PHST- 2014/01/23 00:00 [received]
PHST- 2014/06/30 00:00 [revised]
PHST- 2014/07/03 00:00 [accepted]
PHST- 2014/07/15 06:00 [entrez]
PHST- 2014/07/16 06:00 [pubmed]
PHST- 2015/06/13 06:00 [medline]
AID - S0009-9120(14)00494-9 [pii]
AID - 10.1016/j.clinbiochem.2014.07.002 [doi]
PST - ppublish
SO  - Clin Biochem. 2014 Oct;47(15):33-7. doi: 10.1016/j.clinbiochem.2014.07.002. Epub 
      2014 Jul 12.