PMID- 25027974 OWN - NLM STAT- MEDLINE DCOM- 20150303 LR - 20221207 IS - 1479-5868 (Electronic) IS - 1479-5868 (Linking) VI - 11 DP - 2014 Jul 16 TI - The prospective relationship between sedentary time and cardiometabolic health in adults at increased cardiometabolic risk - the Hoorn Prevention Study. PG - 90 LID - 10.1186/s12966-014-0090-3 [doi] AB - BACKGROUND: Sedentary time has been identified as an important and independent risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) in adults. However, to date most studies have focused on TV time, few also included other sedentary behaviours such as computer use and reading, and most studies had a cross-sectional design. We aimed to examine the prospective relationship between time spent on sedentary behaviours in different domains with individual and clustered cardiometabolic risk in adults. METHODS: Longitudinal data of 622 adults aged 30-50 years (42% males) at increased cardiometabolic risk were used. Leisure time TV viewing, computer use, reading and other sedentary activities (e.g. passive transport) were assessed using a subscale of the Activity Questionnaire for Adolescents and Adults (AQuAA), and summed into overall sedentary behaviour (min/day). Weight and blood pressure were measured, waist-to-hip ratio and BMI calculated, and fasting plasma levels of glucose, HbA1c, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides determined. T2DM risk score was estimated according to the ARIC formula and CVD mortality risk according to the SCORE formula. RESULTS: Generalized Estimating Equation analysis demonstrated that over a two-year period higher levels of overall sedentary time and TV time were weakly but negatively associated with one out of 13 studied cardiometabolic risk factors (i.e. HDL cholesterol). CONCLUSION: Overall sedentary time, as well as sedentary time in different domains, was virtually not related with cardiometabolic risk factors. FAU - Altenburg, Teatske M AU - Altenburg TM FAU - Lakerveld, Jeroen AU - Lakerveld J FAU - Bot, Sandra D AU - Bot SD FAU - Nijpels, Giel AU - Nijpels G FAU - Chinapaw, Mai J M AU - Chinapaw MJ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140716 PL - England TA - Int J Behav Nutr Phys Act JT - The international journal of behavioral nutrition and physical activity JID - 101217089 RN - 0 (Biomarkers) RN - 0 (Blood Glucose) RN - 0 (Cholesterol, HDL) RN - 0 (Cholesterol, LDL) RN - 0 (Glycated Hemoglobin A) RN - 0 (Triglycerides) SB - IM MH - Adult MH - Biomarkers/blood MH - Blood Glucose/metabolism MH - Blood Pressure MH - Body Mass Index MH - Body Weight MH - Cardiovascular Diseases/*prevention & control MH - Cholesterol, HDL/blood MH - Cholesterol, LDL/blood MH - Computers MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/prevention & control MH - Female MH - Glycated Hemoglobin/metabolism MH - Humans MH - Leisure Activities MH - Male MH - Middle Aged MH - Prospective Studies MH - Reading MH - Risk Factors MH - *Sedentary Behavior MH - Surveys and Questionnaires MH - Television MH - Triglycerides/blood MH - Waist Circumference MH - Waist-Hip Ratio PMC - PMC4132212 EDAT- 2014/07/17 06:00 MHDA- 2015/03/04 06:00 PMCR- 2014/07/16 CRDT- 2014/07/17 06:00 PHST- 2013/11/17 00:00 [received] PHST- 2014/06/27 00:00 [accepted] PHST- 2014/07/17 06:00 [entrez] PHST- 2014/07/17 06:00 [pubmed] PHST- 2015/03/04 06:00 [medline] PHST- 2014/07/16 00:00 [pmc-release] AID - s12966-014-0090-3 [pii] AID - 10.1186/s12966-014-0090-3 [doi] PST - epublish SO - Int J Behav Nutr Phys Act. 2014 Jul 16;11:90. doi: 10.1186/s12966-014-0090-3.