PMID- 25030418 OWN - NLM STAT- MEDLINE DCOM- 20150512 LR - 20220311 IS - 1347-4820 (Electronic) IS - 1346-9843 (Linking) VI - 78 IP - 9 DP - 2014 TI - Long-term outcomes of transcatheter closure of ruptured sinus valsalva aneurysms using patent ductus arteriosus occluders. PG - 2197-202 AB - BACKGROUND: Transcatheter closure (TCC) of ruptured sinus of Valsalva aneurysm (RSVA) is an alternative strategy to surgery, but there is a lack of long-term outcome data. METHODS AND RESULTS: From 2004 to 2012, 17 patients (8 males, 9 females) were treated with patent ductus arteriosus (PDA) occluders by antegrade venous approach and were followed for 18-102 months. Of the 17 patients, transthoracic echocardiography revealed rupture of the right coronary sinus into the right ventricle in 9 and into the right atrium in 4, and noncoronary sinus rupture into the right ventricle in 3 and into the right atrium in 1. Most (10/17) were in New York Heart Association (NYHA) functional class III or IV. Aortography showed that the size of the defect was 7.71+/-2.84 mm (4-15 mm). TCC was attempted using PDA occluders 2-5 mm larger than the aortic end of the defects. The device sizes ranged from 8/6 to 18/16 mm (median, 10/8 mm). The procedure was successful in 16 (94.1%), and all of them had complete occlusion at discharge. On a median follow-up of 42 months, 14 patients were in NYHA class I and 2 were in class II, and there was no residual shunt, device embolization, infective endocarditis, or aortic regurgitation. CONCLUSIONS: TCC of RSVA is a safe and effective alternative to surgery with favorable long-term follow-up results. FAU - Fang, Zhen-Fei AU - Fang ZF AD - Department of Cardiology, The Second Xiangya Hospital of Central South University. FAU - Huang, Yi-Yuan AU - Huang YY FAU - Tang, Liang AU - Tang L FAU - Hu, Xin-Qun AU - Hu XQ FAU - Shen, Xiang-Qian AU - Shen XQ FAU - Tang, Jian-Jun AU - Tang JJ FAU - Zhou, Sheng-Hua AU - Zhou SH LA - eng PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140716 PL - Japan TA - Circ J JT - Circulation journal : official journal of the Japanese Circulation Society JID - 101137683 SB - IM MH - Adolescent MH - Adult MH - *Aortic Rupture/etiology/pathology/surgery MH - Aortography/methods MH - Cardiac Catheterization/*methods MH - Child MH - *Ductus Arteriosus, Patent/complications/pathology/surgery MH - Echocardiography/methods MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - *Sinus of Valsalva/pathology/surgery EDAT- 2014/07/18 06:00 MHDA- 2015/05/13 06:00 CRDT- 2014/07/18 06:00 PHST- 2014/07/18 06:00 [entrez] PHST- 2014/07/18 06:00 [pubmed] PHST- 2015/05/13 06:00 [medline] AID - DN/JST.JSTAGE/circj/CJ-14-0106 [pii] AID - 10.1253/circj.cj-14-0106 [doi] PST - ppublish SO - Circ J. 2014;78(9):2197-202. doi: 10.1253/circj.cj-14-0106. Epub 2014 Jul 16.