PMID- 2503470
OWN - NLM
STAT- MEDLINE
DCOM- 19890908
LR  - 20190510
IS  - 0910-5050 (Print)
IS  - 1876-4673 (Electronic)
IS  - 0910-5050 (Linking)
VI  - 80
IP  - 6
DP  - 1989 Jun
TI  - High risk of mother-to-child transmission of HTLV-I in p40tax antibody-positive 
      mothers.
PG  - 506-8
AB  - A new enzyme-linked immunosorbent assay (ELISA) for detecting the antibody to a 
      human T-lymphotropic virus type I (HTLV-I) tax gene product, p40tax, has been 
      developed. By this ELISA method, we have investigated the relationship between 
      the presence of p40tax antibody in HTLV-I-infected mothers and the virus 
      transmission rate from mothers to their children. The rate of mother-to-child 
      transmission of HTLV-I was higher in p40tax antibody-positive mothers than in 
      antibody-negative ones. Thus, the presence of p40tax antibody may indicate an 
      increased risk of vertical transmission of HTLV-I.
FAU - Sawada, T
AU  - Sawada T
AD  - Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki.
FAU - Tohmatsu, J
AU  - Tohmatsu J
FAU - Obara, T
AU  - Obara T
FAU - Koide, A
AU  - Koide A
FAU - Kamihira, S
AU  - Kamihira S
FAU - Ichimaru, M
AU  - Ichimaru M
FAU - Kashiwagi, S
AU  - Kashiwagi S
FAU - Kajiyama, W
AU  - Kajiyama W
FAU - Matsumura, N
AU  - Matsumura N
FAU - Kinoshita, K
AU  - Kinoshita K
AU  - et al.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Jpn J Cancer Res
JT  - Japanese journal of cancer research : Gann
JID - 8509412
RN  - 0 (HTLV-I Antibodies)
RN  - 0 (HTLV-I Antigens)
RN  - 0 (Trans-Activators)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - HTLV-I Antibodies/*analysis
MH  - HTLV-I Antigens/*immunology
MH  - HTLV-I Infections/immunology/*transmission
MH  - Humans
MH  - Lactation
MH  - Middle Aged
MH  - Pregnancy
MH  - Risk Factors
MH  - Trans-Activators
MH  - Transcription Factors/*immunology
PMC - PMC5917792
EDAT- 1989/06/01 00:00
MHDA- 1989/06/01 00:01
PMCR- 1989/06/01
CRDT- 1989/06/01 00:00
PHST- 1989/06/01 00:00 [pubmed]
PHST- 1989/06/01 00:01 [medline]
PHST- 1989/06/01 00:00 [entrez]
PHST- 1989/06/01 00:00 [pmc-release]
AID - CAE506 [pii]
AID - 10.1111/j.1349-7006.1989.tb01667.x [doi]
PST - ppublish
SO  - Jpn J Cancer Res. 1989 Jun;80(6):506-8. doi: 10.1111/j.1349-7006.1989.tb01667.x.