PMID- 25035051
OWN - NLM
STAT- MEDLINE
DCOM- 20150529
LR  - 20211021
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 21
IP  - 24
DP  - 2014 Dec
TI  - Rapid determination of trace dicyandiamide in mussels from Zhejiang coast by 
      ultra-fast liquid chromatography-tandem mass spectrometry with isotope internal 
      standard dilution technique.
PG  - 14219-25
LID - 10.1007/s11356-014-3170-7 [doi]
AB  - In this study, a rapid and accurate ultra-fast liquid chromatography-tandem 
      quadrupole mass spectrometry (UFLC-MS/MS) method coupled with the isotope 
      internal standard dilution technique was established and validated to determine 
      trace dicyandiamide (DCD) in mussels. The sample was extracted by acetonitrile, 
      and chromatographic separations were performed on an Acquity UPLC BEH Amide 
      column by using water-acetonitrile (9:91, v/v) as the mobile phase within 3 min. 
      DCD was determined by using DCD-(15)N4 as an internal standard. The results 
      showed that the recoveries were between 96.2 and 103 % with relative standard 
      deviations (RSDs) in the range of 0.6-6.0 %. The limit of quantification (LOQ) 
      was 0.05 mug/kg. This method can be applied to the routine analysis for the rapid 
      and sensitive determination of trace DCD in mussels. Overall, the data reiterate 
      the importance of investigating the presence of DCD in marine biological samples, 
      which can act as food quality controls for human health.
FAU - Zhang, Yun
AU  - Zhang Y
AD  - Quzhou Center for Disease Control and Prevention, Quzhou, 324000, Zhejiang, 
      China.
FAU - Gong, Wen-Jie
AU  - Gong WJ
FAU - Zhao, Yong-Gang
AU  - Zhao YG
FAU - Zhou, Hua
AU  - Zhou H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140718
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Guanidines)
RN  - 0 (Isotopes)
RN  - 0 (Water Pollutants, Chemical)
RN  - M9B1R0C16H (dicyandiamido)
SB  - IM
MH  - Animals
MH  - Bivalvia/*chemistry
MH  - China
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Analysis/methods
MH  - Guanidines/*analysis
MH  - Humans
MH  - Indicator Dilution Techniques
MH  - Isotopes
MH  - Limit of Detection
MH  - Reference Standards
MH  - Reproducibility of Results
MH  - Tandem Mass Spectrometry/*methods
MH  - Water Pollutants, Chemical/*analysis
EDAT- 2014/07/19 06:00
MHDA- 2015/05/30 06:00
CRDT- 2014/07/19 06:00
PHST- 2013/09/25 00:00 [received]
PHST- 2014/06/06 00:00 [accepted]
PHST- 2014/07/19 06:00 [entrez]
PHST- 2014/07/19 06:00 [pubmed]
PHST- 2015/05/30 06:00 [medline]
AID - 10.1007/s11356-014-3170-7 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2014 Dec;21(24):14219-25. doi: 
      10.1007/s11356-014-3170-7. Epub 2014 Jul 18.