PMID- 25039604
OWN - NLM
STAT- MEDLINE
DCOM- 20150526
LR  - 20220330
IS  - 1529-8027 (Electronic)
IS  - 1085-9489 (Linking)
VI  - 19
IP  - 2
DP  - 2014 Jun
TI  - Genetics of Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating 
      polyradiculoneuropathy (CIDP): current knowledge and future directions.
PG  - 88-103
LID - 10.1111/jns5.12074 [doi]
AB  - Guillain-Barre syndrome (GBS) and chronic inflammatory demyelinating 
      polyradiculoneuropathy (CIDP) are thought to be autoimmune diseases. There have 
      been many attempts to find a human leukocyte antigen (HLA) association with GBS 
      and CIDP with little success. There have been studies of other plausible genes in 
      GBS and CIDP and the role of these genes in GBS and CIDP and the data from these 
      genetic studies is reviewed. Some of the genes that have been studied are immune 
      related and some others have nervous system effects. The studies are limited by 
      small numbers. Some of the genes show association with disease severity rather 
      than disease susceptibility. The need for more detailed molecular studies of the 
      role of HLA molecules and the need for modern genetic approaches to GBS and CIDP 
      are explained.
CI  - (c) 2014 Peripheral Nerve Society.
FAU - Blum, Stefan
AU  - Blum S
AD  - The University of Queensland Centre for Clinical Research, UQ CCR, Queensland, 
      Australia.
FAU - McCombe, Pamela A
AU  - McCombe PA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Peripher Nerv Syst
JT  - Journal of the peripheral nervous system : JPNS
JID - 9704532
RN  - 0 (HLA Antigens)
SB  - IM
MH  - *Genetic Association Studies/methods/trends
MH  - Genetic Predisposition to Disease/*genetics
MH  - Guillain-Barre Syndrome/*genetics
MH  - HLA Antigens/genetics
MH  - Humans
MH  - Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/*genetics
OTO - NOTNLM
OT  - CD1
OT  - Guillain-Barre syndrome
OT  - TNF
OT  - chronic inflammatory demyelinating polyradiculoneuropathy
OT  - disease associations
OT  - genetics
OT  - major histocompatability complex
EDAT- 2014/07/22 06:00
MHDA- 2015/05/27 06:00
CRDT- 2014/07/22 06:00
PHST- 2014/01/14 00:00 [received]
PHST- 2014/03/04 00:00 [revised]
PHST- 2014/04/09 00:00 [accepted]
PHST- 2014/07/22 06:00 [entrez]
PHST- 2014/07/22 06:00 [pubmed]
PHST- 2015/05/27 06:00 [medline]
AID - 10.1111/jns5.12074 [doi]
PST - ppublish
SO  - J Peripher Nerv Syst. 2014 Jun;19(2):88-103. doi: 10.1111/jns5.12074.