PMID- 25039689
OWN - NLM
STAT- MEDLINE
DCOM- 20160115
LR  - 20141110
IS  - 1556-4029 (Electronic)
IS  - 0022-1198 (Linking)
VI  - 59
IP  - 6
DP  - 2014 Nov
TI  - Analysis of ecstasy tablets using capillary electrophoresis with capacitively 
      coupled contactless conductivity detection.
PG  - 1622-6
LID - 10.1111/1556-4029.12573 [doi]
AB  - A method for the identification of 3,4-methylenedioxymethamphetamine (MDMA) and 
      meta-chlorophenylpiperazine (mCPP) was developed employing capillary 
      electrophoresis (CE) with capacitively coupled contactless conductivity detection 
      (C(4) D). Sample extraction, separation, and detection of "Ecstasy" tablets were 
      performed in <10 min without sample derivatization. The separation electrolyte 
      was 20 mm TAPS/Lithium, pH 8.7. Average minimal detectable amounts for MDMA and 
      mCPP were 0.04 mg/tablet, several orders of magnitude lower than the minimum 
      amount encountered in a tablet. Seven different Ecstasy tablets seized in Rio de 
      Janeiro, Brazil, were analyzed by CE-C(4) D and compared against routine gas 
      chromatography-mass spectrometry (GC-MS). The CE method demonstrated sufficient 
      selectivity to discriminate the two target drugs, MDMA and mCPP, from the other 
      drugs present in seizures, namely amphepramone, fenproporex, caffeine, lidocaine, 
      and cocaine. Separation was performed in <90 sec. The advantages of using C(4) D 
      instead of traditional CE-UV methods for in-field analysis are also discussed.
CI  - (c) 2014 American Academy of Forensic Sciences.
FAU - Porto, Suely K S S
AU  - Porto SK
AD  - Departamento de Quimica Fundamental, Instituto de Quimica, Universidade de Sao 
      Paulo, Av. Prof. Lineu Prestes 748, CEP 05508-000, Sao Paulo, SP, Brazil; Servico 
      de Pericias de Quimica, Instituto de Criminalistica Carlos Eboli, R. Pedro I, 28, 
      Rio de Janeiro, RJ, Brazil.
FAU - Nogueira, Thiago
AU  - Nogueira T
FAU - Blanes, Lucas
AU  - Blanes L
FAU - Doble, Philip
AU  - Doble P
FAU - Sabino, Bruno D
AU  - Sabino BD
FAU - do Lago, Claudimir L
AU  - do Lago CL
FAU - Angnes, Lucio
AU  - Angnes L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140721
PL  - United States
TA  - J Forensic Sci
JT  - Journal of forensic sciences
JID - 0375370
RN  - 0 (Hallucinogens)
RN  - 0 (Lithium Compounds)
RN  - 0 (Piperazines)
RN  - 0 (Serotonin Receptor Agonists)
RN  - 0 (Sulfonic Acids)
RN  - 0 (Tablets)
RN  - 29915-38-6 (3-(tris(hydroxymethyl)methylamino)-1-propanesulfonic acid)
RN  - G51XLP968G (lithium hydroxide)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - Q40Q9N063P (Acetic Acid)
RN  - REY0CNO998 (1-(3-chlorophenyl)piperazine)
SB  - IM
MH  - Acetic Acid/chemistry
MH  - Drug Trafficking
MH  - Electric Conductivity
MH  - Electrophoresis, Capillary/*methods
MH  - Gas Chromatography-Mass Spectrometry
MH  - Hallucinogens/*chemistry
MH  - Humans
MH  - Lithium Compounds/chemistry
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*chemistry
MH  - Piperazines/chemistry
MH  - Serotonin Receptor Agonists/chemistry
MH  - Sulfonic Acids/chemistry
MH  - Tablets
OTO - NOTNLM
OT  - 3,4-methylenedioxymethamphetamine
OT  - C4D
OT  - MDMA
OT  - capillary electrophoresis
OT  - contactless conductivity detection
OT  - forensic science
OT  - mCPP
OT  - meta-chlorophenylpiperazine
EDAT- 2014/07/22 06:00
MHDA- 2016/01/16 06:00
CRDT- 2014/07/22 06:00
PHST- 2013/03/20 00:00 [received]
PHST- 2013/11/15 00:00 [revised]
PHST- 2013/12/01 00:00 [accepted]
PHST- 2014/07/22 06:00 [entrez]
PHST- 2014/07/22 06:00 [pubmed]
PHST- 2016/01/16 06:00 [medline]
AID - 10.1111/1556-4029.12573 [doi]
PST - ppublish
SO  - J Forensic Sci. 2014 Nov;59(6):1622-6. doi: 10.1111/1556-4029.12573. Epub 2014 
      Jul 21.