PMID- 25041063 OWN - NLM STAT- MEDLINE DCOM- 20160104 LR - 20220311 IS - 1542-474X (Electronic) IS - 1082-720X (Print) IS - 1082-720X (Linking) VI - 20 IP - 2 DP - 2015 Mar TI - The assessment of relationship between fragmented QRS complex and left ventricular wall motion score index in patients with ST elevation myocardial infarction who underwent primary percutaneous coronary intervention. PG - 148-57 LID - 10.1111/anec.12180 [doi] AB - OBJECTIVES: Fragmented QRS (fQRS) has been found to be associated with high mortality and arrhythmic events in acute coronary syndromes. Regional systolic function using wall motion score index (WMSI) is an alternative to left ventricular ejection fraction (LVEF) for the assessment of left ventricular systolic function. The aim of this study was to investigate the relation between the presence of fQRS on admission electrocardiogram (ECG) and WMSI in ST elevation myocardial infarction (STEMI) underwent primary coronary intervention (PCI). The in-hospital and long-term prognostic significance of persistent fQRS was also evaluated. METHODS: In this retrospective study, 542 patients with a diagnose of STEMI underwent primary PCI were included. Study patients were divided into two groups according to the presence (n = 153) or absence (n = 389) of a fQRS on admission ECG. RESULTS: WMSI was found to be significantly higher in fQRS(+) group compared to the fQRS(-) group (P < 0.001). In multivariete analysis, WMSI was found to be an independent predictor of fQRS, and fQRS was inversely associated with LVEF. The in-hospital reinfarction (P = 0.003), MACE (P = 0.024), intraaortic balloon pump use (P = 0.014), and advanced heart failure (P < 0.001) were found to be significantly more frequent in the fQRS(+) group. The presence of fQRS on admission was found to be associated with an increase in long-term cardiovascular mortality (P = 0.028), and long-term all-cause mortality (P = 0.022). CONCLUSION: WMSI was significantly related with the presence of the fQRS, which reflects the linking between impairment of regional left ventricular systolic function and the presence of severe myocardial injury in STEMI. CI - (c) 2014 Wiley Periodicals, Inc. FAU - Uslu, Nevzat AU - Uslu N AD - Cardiology Department, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Gul, Mehmet AU - Gul M FAU - Cakmak, Huseyin Altug AU - Cakmak HA FAU - Atam, Ali AU - Atam A FAU - Pusuroglu, Hamdi AU - Pusuroglu H FAU - Satilmisoglu, Hulusi AU - Satilmisoglu H FAU - Akkaya, Emre AU - Akkaya E FAU - Aksu, Hale Unal AU - Aksu HU FAU - Kalkan, Ali Kemal AU - Kalkan AK FAU - Surgit, Ozgur AU - Surgit O FAU - Erturk, Mehmet AU - Erturk M FAU - Aksu, Huseyin AU - Aksu H FAU - Eksik, Abdurrahman AU - Eksik A LA - eng PT - Journal Article DEP - 20140717 PL - United States TA - Ann Noninvasive Electrocardiol JT - Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc JID - 9607443 SB - IM CIN - Ann Noninvasive Electrocardiol. 2015 Mar;20(2):198-9. PMID: 25384341 MH - Electrocardiography/*methods MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*physiopathology/*therapy MH - Percutaneous Coronary Intervention/*methods MH - Retrospective Studies MH - Risk Factors MH - Ventricular Function, Left/*physiology PMC - PMC6931736 OTO - NOTNLM OT - fragmented QRS OT - left ventricular systolic function OT - mortality EDAT- 2014/07/22 06:00 MHDA- 2016/01/05 06:00 PMCR- 2014/07/17 CRDT- 2014/07/22 06:00 PHST- 2014/07/22 06:00 [entrez] PHST- 2014/07/22 06:00 [pubmed] PHST- 2016/01/05 06:00 [medline] PHST- 2014/07/17 00:00 [pmc-release] AID - ANEC12180 [pii] AID - 10.1111/anec.12180 [doi] PST - ppublish SO - Ann Noninvasive Electrocardiol. 2015 Mar;20(2):148-57. doi: 10.1111/anec.12180. Epub 2014 Jul 17.