PMID- 25042448
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150512
LR  - 20140801
IS  - 1521-3765 (Electronic)
IS  - 0947-6539 (Linking)
VI  - 20
IP  - 32
DP  - 2014 Aug 4
TI  - A new class of tunable dendritic diphosphine ligands: synthesis and applications 
      in the Ru-catalyzed asymmetric hydrogenation of functionalized ketones.
PG  - 9969-78
LID - 10.1002/chem.201402709 [doi]
AB  - A series of tunable G0-G3 dendritic 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl 
      (BINAP) ligands was prepared by attaching polyaryl ether dendrons onto the four 
      phenyl rings on the P atoms. Their ruthenium complexes were employed in the 
      asymmetric hydrogenation of beta-ketoesters, alpha-ketoesters, and alpha-ketoamides to 
      reveal the effects of dendron size on the catalytic properties. The second- and 
      third-generation catalysts exhibited excellent enantioselectivities, which are 
      remarkably higher than those obtained from the small molecular catalysts and the 
      first-generation catalyst. Molecular modeling indicates that the incorporation of 
      bulky dendritic wedges can influence the steric environments around the metal 
      center. In addition, the ruthenium catalyst bearing a second-generation dendritic 
      ligand could be recycled and reused seven times without any obvious decrease in 
      enantioselectivity.
CI  - (c) 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
FAU - Ma, Baode
AU  - Ma B
AD  - Beijing National Laboratory for Molecular Sciences and CAS Key Laboratory of 
      Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of 
      Sciences (CAS), Beijing 100190 (P.R. China).
FAU - Miao, Tingting
AU  - Miao T
FAU - Sun, Yihua
AU  - Sun Y
FAU - He, Yanmei
AU  - He Y
FAU - Liu, Ji
AU  - Liu J
FAU - Feng, Yu
AU  - Feng Y
FAU - Chen, Hui
AU  - Chen H
FAU - Fan, Qing-Hua
AU  - Fan QH
LA  - eng
PT  - Journal Article
DEP - 20140710
PL  - Germany
TA  - Chemistry
JT  - Chemistry (Weinheim an der Bergstrasse, Germany)
JID - 9513783
OTO - NOTNLM
OT  - asymmetric catalysis
OT  - dendrimers
OT  - hydrogenation
OT  - ligands
OT  - ruthenium
EDAT- 2014/07/22 06:00
MHDA- 2014/07/22 06:01
CRDT- 2014/07/22 06:00
PHST- 2014/03/21 00:00 [received]
PHST- 2014/07/22 06:00 [entrez]
PHST- 2014/07/22 06:00 [pubmed]
PHST- 2014/07/22 06:01 [medline]
AID - 10.1002/chem.201402709 [doi]
PST - ppublish
SO  - Chemistry. 2014 Aug 4;20(32):9969-78. doi: 10.1002/chem.201402709. Epub 2014 Jul 
      10.