PMID- 25042879
OWN - NLM
STAT- MEDLINE
DCOM- 20141110
LR  - 20151119
IS  - 1873-2542 (Electronic)
IS  - 0378-1135 (Linking)
VI  - 172
IP  - 3-4
DP  - 2014 Aug 27
TI  - Synergetic effects of subgroup J avian leukosis virus and reticuloendotheliosis 
      virus co-infection on growth retardation and immunosuppression in SPF chickens.
PG  - 425-31
LID - S0378-1135(14)00317-4 [pii]
LID - 10.1016/j.vetmic.2014.06.025 [doi]
AB  - To further understand the effect of co-infection of subgroup J avian leukosis 
      virus (ALV-J) and reticuloendotheliosis virus (REV) in specific-pathogen-free 
      (SPF) white leghorn chickens, the experiment was made to study the pathogenicity, 
      the weight of body and immune organs, response to newcastle disease virus (NDV) 
      and avian influenza virus subtype H9 (AIV-H9) vaccination. Chickens were randomly 
      divided into four groups, which includes injection groups (REV, ALV-J, REV plus 
      ALV-J), and negative control group. The pathogenesis experiments indicated that 
      chickens co-infected with REV and ALV-J had significantly higher mortality rate 
      than those of the chickens infected with REV or ALV-J alone (P<0.05). Chickens 
      inoculated with REV and ALV-J had significantly lower weights than chickens in 
      all other groups (P<0.05). There were no significant differences between the two 
      single infection groups and co-infection group (P>0.05) on bursa and thymus over 
      body wt ratios, however, chickens co-infected with REV and ALV-J had 
      significantly lower titers than REV-infected chickens and ALV-J-infected chickens 
      on HI antibody titers to ND and AIV-H9 after vaccination (P<0.05). These findings 
      suggested that the co-infection of REV and ALV-J caused more serious growth 
      retardation and immunosuppression in SPF chickens.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Dong, Xuan
AU  - Dong X
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Ju, Sidi
AU  - Ju S
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Zhao, Peng
AU  - Zhao P
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Li, Yang
AU  - Li Y
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Meng, Fanfeng
AU  - Meng F
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Sun, Peng
AU  - Sun P
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China.
FAU - Cui, Zhizhong
AU  - Cui Z
AD  - College of Veterinary Medicine, Shandong Agricultural University, No. 61, Daizong 
      Road, Tai'an 271018, China. Electronic address: zzcui@sdau.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140703
PL  - Netherlands
TA  - Vet Microbiol
JT  - Veterinary microbiology
JID - 7705469
SB  - IM
MH  - Animals
MH  - Avian Leukosis Virus/*classification/isolation & purification
MH  - Bursa of Fabricius/pathology/virology
MH  - *Chickens
MH  - *Coinfection
MH  - Newcastle disease virus
MH  - Poultry Diseases/*virology
MH  - Reticuloendotheliosis virus/*isolation & purification
MH  - Retroviridae Infections/*veterinary/virology
MH  - Specific Pathogen-Free Organisms
MH  - Thymus Gland/pathology/virology
MH  - Tumor Virus Infections/*veterinary/virology
OTO - NOTNLM
OT  - Co-infection
OT  - Reticuloendotheliosis virus (REV)
OT  - Subgroup J of avian leukosis virus (ALV-J)
OT  - Synergism
EDAT- 2014/07/22 06:00
MHDA- 2014/11/11 06:00
CRDT- 2014/07/22 06:00
PHST- 2013/09/21 00:00 [received]
PHST- 2014/06/10 00:00 [revised]
PHST- 2014/06/25 00:00 [accepted]
PHST- 2014/07/22 06:00 [entrez]
PHST- 2014/07/22 06:00 [pubmed]
PHST- 2014/11/11 06:00 [medline]
AID - S0378-1135(14)00317-4 [pii]
AID - 10.1016/j.vetmic.2014.06.025 [doi]
PST - ppublish
SO  - Vet Microbiol. 2014 Aug 27;172(3-4):425-31. doi: 10.1016/j.vetmic.2014.06.025. 
      Epub 2014 Jul 3.