PMID- 25042919
OWN - NLM
STAT- MEDLINE
DCOM- 20150105
LR  - 20140721
IS  - 0253-3758 (Print)
IS  - 0253-3758 (Linking)
VI  - 42
IP  - 5
DP  - 2014 May
TI  - [Association between fragmented QRS complexes and imperfect ST-segment resolution 
      in patients with ST-elevation myocardial infarction after primary percutaneous 
      coronary intervention].
PG  - 400-5
AB  - OBJECTIVE: To explore the relationship between fragmented QRS complexes (fQRS) 
      and imperfect ST-segment resolution in ST elevation myocardial infarction (STEMI) 
      patients undergoing primary percutaneous coronary intervention (p-PCI). METHODS: 
      This study included 227 consecutive patients with STEMI who underwent p-PCI. They 
      were divided into two groups: ECG with fQRS (n = 142) and without fQRS (n = 85). 
      Baseline clinical characteristics,Gensini score, coronary angiography features 
      and the rate of ST-segment resolution were compared between the two groups. 
      RESULTS: (1) Patients with fQRS of ECG had higher cTnI, CK, CK-MB levels and 
      Gensini score, prolonged QRS interval, lower rate of ST-segment resolution and 
      left ventricular ejection fraction (LVEF) than in patients without fQRS (all P < 
      0.01 or P < 0.05). (2) Pearson correlation analysis showed that the rate of 
      ST-segment resolution (r = -0.207, P = 0.002),Gensini score (r = 0.191, P = 
      0.004), LVEF(r = -0.188, P = 0.006), cTnI(r = 0.172, P = 0.010), and the TIMI 
      grade post p-PCI (r = -0.148, P = 0.028) were significantly related with the 
      presence of fQRS. (3) Multivariate logistic regression analysis demonstrated that 
      presence of fQRS at pre-PCI (OR = 2.908, 95%CI:1.095-7.723, P = 0.032) , the 
      number of leads with fQRS before PCI (OR = 1.582, 95%CI:1.250-2.002, P < 0.001), 
      and increased QRS interval (OR = 0.955, 95%CI: 0.924-0.988, P = 0.008) were 
      independent predictors of imperfect ST-segment resolution. CONCLUSIONS: fQRS is 
      related to imperfect ST-segment resolution in STEMI patients undergoing 
      p-PCI.fQRS may be a useful parameter to identify the patients with severe 
      coronary lesion, larger areas of ischemic injury and myocardial infarction as 
      well as severe left ventricular contracted dysfunction.
FAU - Duan, Wenting
AU  - Duan W
AD  - Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 
      300211, China.
FAU - Ma, Xianghong
AU  - Ma X
AD  - Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 
      300211, China. Email: ma_xianghong@163.com.
FAU - Cui, Lijun
AU  - Cui L
AD  - Department of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 
      300211, China.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Xin Xue Guan Bing Za Zhi
JT  - Zhonghua xin xue guan bing za zhi
JID - 7910682
SB  - IM
MH  - Aged
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*physiopathology/therapy
MH  - *Percutaneous Coronary Intervention
EDAT- 2014/07/22 06:00
MHDA- 2015/01/06 06:00
CRDT- 2014/07/22 06:00
PHST- 2014/07/22 06:00 [entrez]
PHST- 2014/07/22 06:00 [pubmed]
PHST- 2015/01/06 06:00 [medline]
PST - ppublish
SO  - Zhonghua Xin Xue Guan Bing Za Zhi. 2014 May;42(5):400-5.