PMID- 25048363
OWN - NLM
STAT- MEDLINE
DCOM- 20150331
LR  - 20211021
IS  - 2151-4658 (Electronic)
IS  - 2151-464X (Print)
IS  - 2151-464X (Linking)
VI  - 67
IP  - 2
DP  - 2015 Feb
TI  - Mapping of the outcome measures in rheumatology core set for antineutrophil 
      cytoplasmic antibody-associated vasculitis to the International Classification of 
      Function, Disability and Health.
PG  - 255-63
LID - 10.1002/acr.22414 [doi]
AB  - OBJECTIVE: The International Classification of Functioning, Disability and Health 
      (ICF) is a framework and classification of health that describes health along 4 
      components: body functions, body structures, activities and participation, and 
      contextual factors. This study examined the content of instruments that 
      constitute the Outcome Measures in Rheumatology (OMERACT) core set of outcome 
      measures for antineutrophil cytoplasmic antibody-associated vasculitis (AAV) by 
      "mapping" them to the ICF. METHODS: The content of the instruments included in 
      the AAV core set were linked to the ICF by 2 independent investigators according 
      to previously established ICF linkage rules. RESULTS: The AAV core set includes 3 
      measures of disease activity (3 versions of the Birmingham Vasculitis Activity 
      Score), 1 damage measure (Vasculitis Damage Index), 1 patient-reported outcome 
      (Short Form 36 health survey), and death. Linking these instruments to the ICF 
      revealed comprehensive coverage of the ICF components body functions and body 
      structures, limited coverage of the ICF component activities and participation, 
      and complete absence of coverage of contextual factors. CONCLUSION: ICF was found 
      to be useful for thematic characterization of a heterogeneous group of outcome 
      measures for AAV, i.e., a group of complex medical conditions. Linking of the 
      instruments selected for the OMERACT AAV core set of outcome measures to the ICF 
      classification revealed limitations in the representation of constructs related 
      to life impact of AAV, represented by the ICF components activities and 
      participation and contextual factors. Further research and methods development 
      are needed to better incorporate important aspects of functioning and health 
      relevant to patients into clinical trials of AAV.
CI  - Copyright (c) 2015 by the American College of Rheumatology.
FAU - Milman, Nataliya
AU  - Milman N
AD  - Ottawa Hospital and University of Ottawa, Ottawa, Ontario, Canada.
FAU - Boonen, Annelies
AU  - Boonen A
FAU - Merkel, Peter A
AU  - Merkel PA
FAU - Tugwell, Peter
AU  - Tugwell P
LA  - eng
GR  - U54 AR-057319/AR/NIAMS NIH HHS/United States
GR  - U01 AR051874/AR/NIAMS NIH HHS/United States
GR  - U54-RR-019497/RR/NCRR NIH HHS/United States
GR  - U54 RR019497/RR/NCRR NIH HHS/United States
GR  - U01-AR-51874 04/AR/NIAMS NIH HHS/United States
GR  - U54 AR057319/AR/NIAMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Arthritis Care Res (Hoboken)
JT  - Arthritis care & research
JID - 101518086
SB  - IM
MH  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*classification
MH  - Humans
MH  - *Outcome Assessment, Health Care
MH  - *Rheumatology
PMC - PMC4505813
MID - NIHMS703984
EDAT- 2014/07/23 06:00
MHDA- 2015/04/01 06:00
PMCR- 2015/08/01
CRDT- 2014/07/23 06:00
PHST- 2014/01/22 00:00 [received]
PHST- 2014/07/15 00:00 [accepted]
PHST- 2014/07/23 06:00 [entrez]
PHST- 2014/07/23 06:00 [pubmed]
PHST- 2015/04/01 06:00 [medline]
PHST- 2015/08/01 00:00 [pmc-release]
AID - 10.1002/acr.22414 [doi]
PST - ppublish
SO  - Arthritis Care Res (Hoboken). 2015 Feb;67(2):255-63. doi: 10.1002/acr.22414.