PMID- 25048374 OWN - NLM STAT- MEDLINE DCOM- 20150316 LR - 20211021 IS - 1476-1645 (Electronic) IS - 0002-9637 (Print) IS - 0002-9637 (Linking) VI - 91 IP - 4 DP - 2014 Oct TI - Asymptomatic intestinal amebiasis in Japanese HIV-1-infected individuals. PG - 816-20 LID - 10.4269/ajtmh.14-0278 [doi] AB - Seventy-one asymptomatic human immunodeficiency virus-1 (HIV-1) -infected individuals who underwent colonoscopy for detection of diseases other than amebiasis were included in this study. Ulcerative lesions caused by Entamoeba histolytica were identified by colonoscopy and biopsy in 11.3% (8 of 71) of individuals. Stool microscopic examination hardly identified Entamoeba, whereas serum antibody against E. histolytica was often elevated in patients with subclinical intestinal amebiasis. Human leukocyte antigen (HLA) class II allele against E. histolytica infection (DQB1*06:01) was frequently identified in these patients. This study emphasizes the endemic nature of E. histolytica infection in our cohort and the difficulties in epidemiological control. CI - (c) The American Society of Tropical Medicine and Hygiene. FAU - Watanabe, Koji AU - Watanabe K AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Nagata, Naoyoshi AU - Nagata N AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Sekine, Katsunori AU - Sekine K AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Watanabe, Kazuhiro AU - Watanabe K AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Igari, Toru AU - Igari T AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Tanuma, Junko AU - Tanuma J AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Kikuchi, Yoshimi AU - Kikuchi Y AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Oka, Shinichi AU - Oka S AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan. FAU - Gatanaga, Hiroyuki AU - Gatanaga H AD - AIDS Clinical Center, Department of Gastroenterology and Hepatology, and Pathology Division of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan; Center for AIDS Research, Kumamoto University, Kumamoto, Japan higatana@acc.ncgm.go.jp. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140721 PL - United States TA - Am J Trop Med Hyg JT - The American journal of tropical medicine and hygiene JID - 0370507 RN - 0 (Antibodies, Protozoan) RN - 0 (HLA-DQ beta-Chains) RN - 0 (HLA-DQB1 antigen) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Antibodies, Protozoan/blood MH - Asymptomatic Diseases MH - Biopsy MH - Cohort Studies MH - Colonoscopy MH - Cross-Sectional Studies MH - Entamoeba histolytica/immunology/*isolation & purification MH - Entamoebiasis/*complications/immunology/parasitology MH - Feces/parasitology MH - Female MH - Gene Frequency MH - HIV Infections/*complications/immunology/virology MH - HIV-1/*isolation & purification MH - HLA-DQ beta-Chains/blood/genetics MH - Humans MH - Intestinal Diseases/*complications/immunology/parasitology MH - Japan MH - Male MH - Middle Aged MH - Prevalence MH - Ulcer/*complications/epidemiology/parasitology PMC - PMC4183411 EDAT- 2014/07/23 06:00 MHDA- 2015/03/17 06:00 PMCR- 2015/10/01 CRDT- 2014/07/23 06:00 PHST- 2014/07/23 06:00 [entrez] PHST- 2014/07/23 06:00 [pubmed] PHST- 2015/03/17 06:00 [medline] PHST- 2015/10/01 00:00 [pmc-release] AID - ajtmh.14-0278 [pii] AID - 10.4269/ajtmh.14-0278 [doi] PST - ppublish SO - Am J Trop Med Hyg. 2014 Oct;91(4):816-20. doi: 10.4269/ajtmh.14-0278. Epub 2014 Jul 21.