PMID- 25052046 OWN - NLM STAT- MEDLINE DCOM- 20160125 LR - 20200930 IS - 1552-4981 (Electronic) IS - 1552-4973 (Linking) VI - 103 IP - 4 DP - 2015 May TI - Preparation, mechanical, and in vitro properties of glass fiber-reinforced polycarbonate composites for orthodontic application. PG - 743-50 LID - 10.1002/jbm.b.33245 [doi] AB - Generally, orthodontic treatment uses metallic wires made from stainless steel, cobalt-chromium-nickel alloy, beta-titanium alloy, and nickel-titanium (Ni-Ti) alloy. However, these wires are not esthetically pleasing and may induce allergic or toxic reactions. To correct these issues, in the present study we developed glass-fiber-reinforced plastic (GFRP) orthodontic wires made from polycarbonate and E-glass fiber by using pultrusion. After fabricating these GFRP round wires with a diameter of 0.45 mm (0.018 inch), we examined their mechanical and in vitro properties. To investigate how the glass-fiber diameter affected their physical properties, we prepared GFRP wires of varying diameters (7 and 13 microm). Both the GFRP with 13-microm fibers (GFRP-13) and GFRP with 7 microm fibers (GFRP-7) were more transparent than the metallic orthodontic wires. Flexural strengths of GFRP-13 and GFRP-7 were 690.3 +/- 99.2 and 938.1 +/- 95.0 MPa, respectively; flexural moduli of GFRP-13 and GFRP-7 were 25.4 +/- 4.9 and 34.7 +/- 7.7 GPa, respectively. These flexural properties of the GFRP wires were nearly equivalent to those of available Ni-Ti wires. GFRP-7 had better flexural properties than GFRP-13, indicating that the flexural properties of GFRP increase with decreasing fiber diameter. Using thermocycling, we found no significant change in the flexural properties of the GFRPs after 600 or 1,200 cycles. Using a cytotoxicity detection kit, we found that the glass fiber and polycarbonate components comprising the GFRP were not cytotoxic within the limitations of this study. We expect this metal-free GFRP wire composed of polycarbonate and glass fiber to be useful as an esthetically pleasing alternative to current metallic orthodontic wire. CI - (c) 2014 Wiley Periodicals, Inc. FAU - Tanimoto, Yasuhiro AU - Tanimoto Y AD - Department of Dental Biomaterials, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho Nishi, Matsudo, Chiba, 271-8587, Japan. FAU - Inami, Toshihiro AU - Inami T FAU - Yamaguchi, Masaru AU - Yamaguchi M FAU - Nishiyama, Norihiro AU - Nishiyama N FAU - Kasai, Kazutaka AU - Kasai K LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140723 PL - United States TA - J Biomed Mater Res B Appl Biomater JT - Journal of biomedical materials research. Part B, Applied biomaterials JID - 101234238 RN - 0 (Polycarboxylate Cement) RN - 0 (fiberglass) RN - 25766-59-0 (polycarbonate) SB - IM MH - Fibroblasts/cytology/*metabolism MH - Glass/*chemistry MH - Humans MH - *Materials Testing MH - *Orthodontic Wires MH - Polycarboxylate Cement/*chemistry OTO - NOTNLM OT - biomechanics OT - fiber-reinforced composite OT - in vitro OT - mechanical properties OT - orthodontic EDAT- 2014/07/24 06:00 MHDA- 2016/01/26 06:00 CRDT- 2014/07/24 06:00 PHST- 2014/02/13 00:00 [received] PHST- 2014/06/15 00:00 [revised] PHST- 2014/07/05 00:00 [accepted] PHST- 2014/07/24 06:00 [entrez] PHST- 2014/07/24 06:00 [pubmed] PHST- 2016/01/26 06:00 [medline] AID - 10.1002/jbm.b.33245 [doi] PST - ppublish SO - J Biomed Mater Res B Appl Biomater. 2015 May;103(4):743-50. doi: 10.1002/jbm.b.33245. Epub 2014 Jul 23.