PMID- 25059843
OWN - NLM
STAT- MEDLINE
DCOM- 20151030
LR  - 20240325
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 4
DP  - 2014 Jul 25
TI  - Serial changes of humor comprehension for four-frame comic Manga: an fMRI study.
PG  - 5828
LID - 10.1038/srep05828 [doi]
LID - 5828
AB  - Serial changes of humor comprehension evoked by a well organized four-frame comic 
      Manga were investigated by fMRI in each step of humor comprehension. The neural 
      substrates underlying the amusing effects in response to funny and mixed order 
      manga were compared. In accordance with the time course of the four frames, fMRI 
      activations changed serially. Beginning with the second frame (development 
      scene), activation of the temporo-parietal junction (TPJ) was observed, followed 
      by activations in the temporal and frontal areas during viewing of the third 
      frame (turn scene). For the fourth frame (punch line), strong increased 
      activations were confirmed in the medial prefrontal cortex (MPFC) and cerebellum. 
      Interestingly, distinguishable activation differences in the cerebellum between 
      funny and non-funny conditions were also found for the fourth frame. These 
      findings suggest that humor comprehension evokes activation that initiates in the 
      TPJ and expands to the MPFC and cerebellum at the convergence level.
FAU - Osaka, Mariko
AU  - Osaka M
AD  - Graduate School of Human Sciences, Osaka University.
FAU - Yaoi, Ken
AU  - Yaoi K
AD  - Graduate School of Letters, Kyoto University.
FAU - Minamoto, Takehiro
AU  - Minamoto T
AD  - Graduate School of Human Sciences, Osaka University.
FAU - Osaka, Naoyuki
AU  - Osaka N
AD  - Graduate School of Letters, Kyoto University.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140725
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Adult
MH  - Brain/*diagnostic imaging
MH  - Brain Mapping
MH  - Cerebellum/physiology
MH  - Comprehension/*physiology
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Radiography
PMC - PMC5376052
COIS- The authors declare no competing financial interests.
EDAT- 2014/07/26 06:00
MHDA- 2015/10/31 06:00
PMCR- 2014/07/25
CRDT- 2014/07/26 06:00
PHST- 2013/10/09 00:00 [received]
PHST- 2014/07/03 00:00 [accepted]
PHST- 2014/07/26 06:00 [entrez]
PHST- 2014/07/26 06:00 [pubmed]
PHST- 2015/10/31 06:00 [medline]
PHST- 2014/07/25 00:00 [pmc-release]
AID - srep05828 [pii]
AID - 10.1038/srep05828 [doi]
PST - epublish
SO  - Sci Rep. 2014 Jul 25;4:5828. doi: 10.1038/srep05828.