PMID- 25062898 OWN - NLM STAT- MEDLINE DCOM- 20150731 LR - 20181202 IS - 1743-9159 (Electronic) IS - 1743-9159 (Linking) VI - 12 IP - 9 DP - 2014 TI - Is the LINX reflux management system an effective treatment for gastro-oesophageal reflux disease? PG - 994-7 LID - S1743-9191(14)00223-4 [pii] LID - 10.1016/j.ijsu.2014.07.016 [doi] AB - A best evidence topic in surgery was written according to a structured protocol. The question addressed whether LINX Reflux management system is an efficacious treatment for patients with symptoms of gastro-oesophageal reflux disease (GORD) not controlled by proton pump inhibitors (PPI). Forty-eight LINX-related papers were identified using the reported search, of which three represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group, study type, relevant outcomes and results of these papers are tabulated. All three studies were prospective case studies. They demonstrated that LINX is an efficacious treatment for GORD patients with good short and medium term outcomes and an acceptable safety profile. Further studies are required to determine its long term outcomes and its relative efficacy as compared to other established treatments. CI - Copyright (c) 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved. FAU - Loh, Yiwen AU - Loh Y AD - Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK. FAU - McGlone, Emma Rose AU - McGlone ER AD - Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK. FAU - Reddy, Marcus AU - Reddy M AD - Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK. FAU - Khan, Omar A AU - Khan OA AD - Department of Upper GI Surgery, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK. Electronic address: okhan342@gmail.com. LA - eng PT - Journal Article PT - Review DEP - 20140722 PL - United States TA - Int J Surg JT - International journal of surgery (London, England) JID - 101228232 RN - 0 (Gastrointestinal Agents) RN - 0 (Proton Pump Inhibitors) SB - IM MH - Gastroesophageal Reflux/drug therapy/*surgery MH - Gastrointestinal Agents/therapeutic use MH - Humans MH - Magnetic Field Therapy/*instrumentation MH - Prospective Studies MH - Proton Pump Inhibitors/therapeutic use MH - Treatment Outcome OTO - NOTNLM OT - GERD OT - GORD OT - LINX OT - MSA OT - Magnetic sphincter augmentation OT - Magnetic sphincter device EDAT- 2014/07/27 06:00 MHDA- 2015/08/01 06:00 CRDT- 2014/07/27 06:00 PHST- 2014/05/24 00:00 [received] PHST- 2014/06/13 00:00 [revised] PHST- 2014/07/21 00:00 [accepted] PHST- 2014/07/27 06:00 [entrez] PHST- 2014/07/27 06:00 [pubmed] PHST- 2015/08/01 06:00 [medline] AID - S1743-9191(14)00223-4 [pii] AID - 10.1016/j.ijsu.2014.07.016 [doi] PST - ppublish SO - Int J Surg. 2014;12(9):994-7. doi: 10.1016/j.ijsu.2014.07.016. Epub 2014 Jul 22.