PMID- 25065093 OWN - NLM STAT- MEDLINE DCOM- 20140825 LR - 20140728 IS - 0125-2208 (Print) IS - 0125-2208 (Linking) VI - 97 IP - 5 DP - 2014 May TI - Oral rehydration with 10% carbohydrate drink for preventing postoperative nausea and vomiting (PONV) after low dose of spinal morphine. PG - 530-5 AB - BACKGROUND: Preoperative oral carbohydrate (CHO) drink may improve patients' comfort. However, whether it prevents or reduces postoperative nausea and vomiting (PONV) is questionable. OBJECTIVE: Evaluate the effect of oral rehydration with 10% CHO drink before anesthesia on incidence and severity of postoperative nausea and vomiting (PONV) after spinal morphine injection. MATERIAL AND METHOD: One hundred patients scheduled for unilateral total knee replacement (TKR) were randomly divided into two equal groups (n = 50 each). Group I patients received 400 ml 10% CHO drink the preoperative night and 2-hour before anesthesia, whereas Group II patients served as control. Spinal anesthesia for all patients contained 0.5% bupivacaine 2.0 to 3.5 ml plus morphine 0.2 mg. Pain therapy was standardized with femoral nerve block, local infiltration, intravenous parecoxib, and oral paracetamol. Incidence and severity of PONV within 24 hours were recorded In addition, preoperative intensity of thirst and hunger, dry lips and throat, and anxiety was also recorded RESULTS: Incidence and severity of PONV (81.2% vs. 72.0%, p = 0.536) as well as preoperative thirst, hunger dry lips, and throat were not different between the groups. CONCLUSION: Preoperative oral rehydration with carbohydrate drinks had no positive effect on PONV nor patients' comfort. FAU - Raksakietisak, Manee AU - Raksakietisak M FAU - Chinachoti, Tithima AU - Chinachoti T FAU - Iamaroon, Arissara AU - Iamaroon A FAU - Thabpenthai, Yos AU - Thabpenthai Y FAU - Halilamien, Pathom AU - Halilamien P FAU - Siriratwarangkul, Sasiya AU - Siriratwarangkul S FAU - Watanitanon, Arraya AU - Watanitanon A LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - Thailand TA - J Med Assoc Thai JT - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JID - 7507216 RN - 0 (Analgesics, Opioid) RN - 0 (Antiemetics) RN - 0 (Dietary Carbohydrates) RN - 76I7G6D29C (Morphine) SB - IM MH - Aged MH - Aged, 80 and over MH - Analgesics, Opioid/*administration & dosage MH - Antiemetics/*administration & dosage MH - *Beverages MH - Dietary Carbohydrates/*administration & dosage MH - Female MH - Fluid Therapy/*methods MH - Humans MH - Injections, Spinal MH - Male MH - Middle Aged MH - Morphine/*administration & dosage MH - Postoperative Nausea and Vomiting/*prevention & control MH - Prospective Studies MH - Treatment Outcome EDAT- 2014/07/30 06:00 MHDA- 2014/08/26 06:00 CRDT- 2014/07/29 06:00 PHST- 2014/07/29 06:00 [entrez] PHST- 2014/07/30 06:00 [pubmed] PHST- 2014/08/26 06:00 [medline] PST - ppublish SO - J Med Assoc Thai. 2014 May;97(5):530-5.