PMID- 25069086 OWN - NLM STAT- MEDLINE DCOM- 20141007 LR - 20170827 IS - 1873-6424 (Electronic) IS - 0269-7491 (Linking) VI - 193 DP - 2014 Oct TI - Levels and profile of several classes of organic contaminants in matched indoor dust and serum samples from occupational settings of Pakistan. PG - 269-276 LID - S0269-7491(14)00299-1 [pii] LID - 10.1016/j.envpol.2014.07.009 [doi] AB - Dust ingestion is an important route of human exposure to organic contaminants, especially for flame retardants (FRs) in occupational settings. Several classes of organic contaminants were analyzed in matched dust and serum samples from academics and workers in electronics and clothing stores of Faisalabad, Pakistan. The concentrations of contaminants varied in dust as follow: organophosphate FRs ( summation operatorPFRs) > novel brominated FRs ( summation operatorNBFRs) > polybrominated diphenyl ethers ( summation operatorPBDEs) > organochlorine pesticides ( summation operatorOCPs) > polychlorinated biphenyls ( summation operatorPCBs), while, in serum, concentration varied: summation operatorOCPs > bromophenols ( summation operatorBPs) > summation operatorPCBs > summation operatorHO-PCBs approximately summation operatorPBDEs. Two NBFRs, namely 1,2-bis(2,4,6-tribromophenoxy)-ethane (BTBPE) and bis(2-ethylhexyl) tetrabromophthalate (TBPH), were detected in <10% of the serum samples. p,p'-DDE was the major contaminant in serum contributing to approximately 75% of the total contaminant burden. Levels of Penta-BDE congeners in serum and dust were significantly correlated (r = 0.64, p < 0.01) for the academics, suggesting dust ingestion as an important determinant for their serum levels. CI - Copyright (c) 2014 Elsevier Ltd. All rights reserved. FAU - Ali, Nadeem AU - Ali N AD - Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium; Center of Excellence in Environmental Studies, King Abdulaziz University, Jeddah, Saudi Arabia. FAU - Mehdi, Toufeer AU - Mehdi T AD - Microbiology Division, Agriculture and Agri-Food Canada, Lacombe, Alberta, Canada. FAU - Malik, Riffat N AU - Malik RN AD - Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Quiad-i-Azam University, Islamabad 45320, Pakistan. FAU - Eqani, Syed A M A S AU - Eqani SAMAS AD - Department of BioSciences, COMSATS Institute of Information Technology, Park Road, Islamabad, Pakistan. FAU - Kamal, Atif AU - Kamal A AD - Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Quiad-i-Azam University, Islamabad 45320, Pakistan. FAU - Dirtu, Alin C AU - Dirtu AC AD - Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium. FAU - Neels, Hugo AU - Neels H AD - Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium. FAU - Covaci, Adrian AU - Covaci A AD - Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium. Electronic address: adrian.covaci@uantwerpen.be. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140726 PL - England TA - Environ Pollut JT - Environmental pollution (Barking, Essex : 1987) JID - 8804476 RN - 0 (Dust) RN - 0 (Flame Retardants) RN - 0 (Halogenated Diphenyl Ethers) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Organophosphates) RN - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Air Pollution, Indoor/*analysis MH - Dichlorodiphenyl Dichloroethylene/analysis/blood MH - Dust/*analysis MH - Flame Retardants/*analysis MH - Halogenated Diphenyl Ethers/analysis/blood MH - Humans MH - Hydrocarbons, Chlorinated/analysis/blood MH - Occupational Exposure/*analysis MH - Organophosphates/analysis/blood MH - Pakistan MH - Polychlorinated Biphenyls/analysis/blood OTO - NOTNLM OT - Dust OT - Occupational settings OT - Organic contaminants OT - Pakistan OT - Serum EDAT- 2014/07/30 06:00 MHDA- 2014/10/08 06:00 CRDT- 2014/07/29 06:00 PHST- 2014/04/18 00:00 [received] PHST- 2014/06/28 00:00 [revised] PHST- 2014/07/01 00:00 [accepted] PHST- 2014/07/29 06:00 [entrez] PHST- 2014/07/30 06:00 [pubmed] PHST- 2014/10/08 06:00 [medline] AID - S0269-7491(14)00299-1 [pii] AID - 10.1016/j.envpol.2014.07.009 [doi] PST - ppublish SO - Environ Pollut. 2014 Oct;193:269-276. doi: 10.1016/j.envpol.2014.07.009. Epub 2014 Jul 26.