PMID- 25070996 OWN - NLM STAT- MEDLINE DCOM- 20150316 LR - 20211021 IS - 1476-1645 (Electronic) IS - 0002-9637 (Print) IS - 0002-9637 (Linking) VI - 91 IP - 4 DP - 2014 Oct TI - Clinical outcome and immune follow-up of different surgical approaches for human cyst hydatid disease in liver. PG - 801-5 LID - 10.4269/ajtmh.14-0177 [doi] AB - A new surgical approach (subadventitial cystectomy) has been developed for liver hydatid disease. We retrospectively compared clinical outcomes and immune status 24 months after a subadventitial cystectomy with traditional surgical approaches. Patients with liver hydatid cysts were treated with a subadventitial cystectomy (N = 11), pericystectomy (N = 16), partial pericystectomy (N = 18), or hepatic resection (N = 12). By the end of the follow-up period, the subadventitial cystectomy group had the fewest post-operative complications and shortest hospital stays. Two recurrences occurred: one recurrence after partial pericystectomy and one recurrence after pericystectomy. The total immunoglobulin E (IgE) level decreased significantly in the subadventitial cystectomy group. The post-surgery IgG level was lower in the subadventitial cystectomy than the pericystectomy and partial pericystectomy groups. In conclusion, subadventitial cystectomy completely removes the parasite, causing lower complication rates and lower immune reactions. CI - (c) The American Society of Tropical Medicine and Hygiene. FAU - Chen, Xinhua AU - Chen X AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. FAU - Chen, Xinmei AU - Chen X AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. FAU - Shao, Yingmei AU - Shao Y AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. FAU - Zhao, Jingming AU - Zhao J AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. FAU - Li, Haitao AU - Li H AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. FAU - Wen, Hao AU - Wen H AD - Department of Hepatobiliary Surgery, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan Shandong, China; Xinjiang Key Laboratory of Echinococcosis, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China wenhao@superinfo.info. LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20140728 PL - United States TA - Am J Trop Med Hyg JT - The American journal of tropical medicine and hygiene JID - 0370507 RN - 0 (Anticestodal Agents) RN - 0 (Immunoglobulin G) RN - 37341-29-0 (Immunoglobulin E) RN - F4216019LN (Albendazole) SB - IM MH - Adult MH - Albendazole/therapeutic use MH - Animals MH - Anticestodal Agents/therapeutic use MH - Cystectomy/*methods MH - Echinococcosis, Hepatic/immunology/parasitology/*surgery MH - Echinococcus/*isolation & purification MH - Female MH - Follow-Up Studies MH - Humans MH - Immunoglobulin E/blood MH - Immunoglobulin G/blood MH - Length of Stay MH - Liver/immunology/parasitology/*surgery MH - Male MH - Middle Aged MH - Recurrence MH - Retrospective Studies PMC - PMC4183408 EDAT- 2014/07/30 06:00 MHDA- 2015/03/17 06:00 PMCR- 2015/10/01 CRDT- 2014/07/30 06:00 PHST- 2014/07/30 06:00 [entrez] PHST- 2014/07/30 06:00 [pubmed] PHST- 2015/03/17 06:00 [medline] PHST- 2015/10/01 00:00 [pmc-release] AID - ajtmh.14-0177 [pii] AID - 10.4269/ajtmh.14-0177 [doi] PST - ppublish SO - Am J Trop Med Hyg. 2014 Oct;91(4):801-5. doi: 10.4269/ajtmh.14-0177. Epub 2014 Jul 28.