PMID- 25078351 OWN - NLM STAT- MEDLINE DCOM- 20150828 LR - 20211021 IS - 1435-702X (Electronic) IS - 0721-832X (Linking) VI - 253 IP - 3 DP - 2015 Mar TI - Relationship between foveal microstructures and visual outcomes in eyes with resolved central serous chorioretinopathy. PG - 343-50 LID - 10.1007/s00417-014-2695-2 [doi] AB - PURPOSE: To determine whether significant correlations exist between the foveal microstructures and visual outcomes in eyes with resolved central serous chorioretinopathy (CSC). METHODS: We retrospectively reviewed the medical records of patients who had a complete resolution of the serous retinal detachment (SRD) and had an intact ellipsoid zone in the fovea in the spectral-domain optical coherence tomographic (SD-OCT) images. Twenty-five eyes with CSC (CSC group) and 18 unaffected fellow eyes (control group) of 23 patients were evaluated. The eyes in the CSC group were divided into those with (n = 11) and those without (n = 14) visual disturbances after resolution of the SRD. The thickness of each retinal layer at the fovea was measured in the SD-OCT images. RESULTS: The photoreceptor outer segment (OS) length in the CSC group was significantly shorter than that in the control group (p = 0.0003). In addition, the photoreceptor OS length in the visual disturbances group was significantly shorter and the duration of SRD was significantly longer than that in the no visual disturbances group (p = 0.0230, p = 0.0021, respectively). CONCLUSIONS: The photoreceptor OS length is a good parameter to indicate the integrity of the foveal photoreceptors in eyes with a resolved CSC. FAU - Hasegawa, Taiji AU - Hasegawa T AD - Department of Ophthalmology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan, taijiha@naramed-u.ac.jp. FAU - Okamoto, Masahiro AU - Okamoto M FAU - Masuda, Naonori AU - Masuda N FAU - Ueda, Tetsuo AU - Ueda T FAU - Ogata, Nahoko AU - Ogata N LA - eng PT - Comparative Study PT - Journal Article DEP - 20140731 PL - Germany TA - Graefes Arch Clin Exp Ophthalmol JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie JID - 8205248 SB - IM MH - Adult MH - Central Serous Chorioretinopathy/diagnosis/*physiopathology MH - Female MH - Fluorescein Angiography MH - Follow-Up Studies MH - Fovea Centralis MH - Humans MH - Male MH - Middle Aged MH - Observer Variation MH - Retinal Detachment/diagnosis/physiopathology MH - Retinal Photoreceptor Cell Outer Segment/*pathology MH - Retrospective Studies MH - Tomography, Optical Coherence MH - Visual Acuity/*physiology EDAT- 2014/08/01 06:00 MHDA- 2015/09/01 06:00 CRDT- 2014/08/01 06:00 PHST- 2014/04/13 00:00 [received] PHST- 2014/06/10 00:00 [accepted] PHST- 2014/06/03 00:00 [revised] PHST- 2014/08/01 06:00 [entrez] PHST- 2014/08/01 06:00 [pubmed] PHST- 2015/09/01 06:00 [medline] AID - 10.1007/s00417-014-2695-2 [doi] PST - ppublish SO - Graefes Arch Clin Exp Ophthalmol. 2015 Mar;253(3):343-50. doi: 10.1007/s00417-014-2695-2. Epub 2014 Jul 31.