PMID- 25078391
OWN - NLM
STAT- MEDLINE
DCOM- 20150105
LR  - 20141106
IS  - 1432-8798 (Electronic)
IS  - 0304-8608 (Linking)
VI  - 159
IP  - 12
DP  - 2014 Dec
TI  - Development of a tetra-primer ARMS PCR-based assay for detection of a novel 
      single-nucleotide polymorphism in the 5' untranslated region of the bovine ITGB6 
      receptor gene associated with foot-and-mouth disease susceptibility in cattle.
PG  - 3385-9
LID - 10.1007/s00705-014-2194-0 [doi]
AB  - ITGB6 is known to be one of the major receptor components involved in host 
      tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR 
      technique called ARMS PCR was adapted to identify a single-nucleotide 
      polymorphism (SNP), G29A, db SNP Id: rs109075046, in the 5' untranslated region 
      (5'UTR) of the bovine ITGB6 gene. Genotype profiling identified three kinds of 
      genetic variation within the targeted SNP among Frieswal crossbred cattle. The 
      occurrence of FMD in the three genotypes was further evaluated, revealing a clear 
      role in the incidence of FMD in the studied population.
FAU - Singh, Rani
AU  - Singh R
AD  - Molecular Genetic Laboratory, Animal Genetic and Breeding Division, Central 
      Institute for Research on Cattle (formerly Project Directorate on Cattle), Meerut 
      Cantt, 250001, Uttar Pradesh, India.
FAU - Deb, Rajib
AU  - Deb R
FAU - Singh, Umesh
AU  - Singh U
FAU - Alex, Rani
AU  - Alex R
FAU - Kumar, Sushil
AU  - Kumar S
FAU - Chakraborti, Soumendu
AU  - Chakraborti S
FAU - Sharma, Sheetal
AU  - Sharma S
FAU - Sengar, Gyanendra
AU  - Sengar G
FAU - Singh, Rupali
AU  - Singh R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20140731
PL  - Austria
TA  - Arch Virol
JT  - Archives of virology
JID - 7506870
RN  - 0 (5' Untranslated Regions)
RN  - 0 (DNA Primers)
SB  - IM
MH  - *5' Untranslated Regions
MH  - Animals
MH  - Cattle
MH  - Cattle Diseases/*genetics
MH  - DNA Primers/genetics
MH  - Foot-and-Mouth Disease/*genetics
MH  - *Genetic Predisposition to Disease
MH  - Polymerase Chain Reaction/*methods
MH  - *Polymorphism, Single Nucleotide
EDAT- 2014/08/01 06:00
MHDA- 2015/01/06 06:00
CRDT- 2014/08/01 06:00
PHST- 2014/05/31 00:00 [received]
PHST- 2014/07/21 00:00 [accepted]
PHST- 2014/08/01 06:00 [entrez]
PHST- 2014/08/01 06:00 [pubmed]
PHST- 2015/01/06 06:00 [medline]
AID - 10.1007/s00705-014-2194-0 [doi]
PST - ppublish
SO  - Arch Virol. 2014 Dec;159(12):3385-9. doi: 10.1007/s00705-014-2194-0. Epub 2014 
      Jul 31.