PMID- 25084689
OWN - NLM
STAT- MEDLINE
DCOM- 20150612
LR  - 20211021
IS  - 1873-4499 (Electronic)
IS  - 0899-7071 (Print)
IS  - 0899-7071 (Linking)
VI  - 38
IP  - 6
DP  - 2014 Nov-Dec
TI  - Isolated intracerebral light chain deposition disease: novel imaging and 
      pathologic findings.
PG  - 868-71
LID - S0899-7071(14)00164-8 [pii]
LID - 10.1016/j.clinimag.2014.06.015 [doi]
AB  - Light chain deposition disease (LCDD) is a rare clinicopathologic entity first 
      described in 1976 and is characterized by a monoclonal gammopathy resulting in 
      nonamyloid immunoglobulin light chain tissue deposition. Only four cases of 
      intracerebral LCDD have been previously reported, all in the setting of a known 
      plasma cell dyscrasia or in the presence of local mature plasma cells. We present 
      the first case of intracranial LCDD in the absence of a known plasma cell 
      dyscrasia or local mature plasma cells.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Yu, John-Paul J
AU  - Yu JP
AD  - University of California, San Francisco, Department of Radiology and Biomedical 
      Imaging, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628. Electronic 
      address: jp.yu@ucsf.edu.
FAU - Wilson, David M
AU  - Wilson DM
AD  - University of California, San Francisco, Department of Radiology and Biomedical 
      Imaging, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
FAU - Chang, Edward F
AU  - Chang EF
AD  - University of California, San Francisco, Departments of Neurological Surgery and 
      Physiology and Center for Integrative Neuroscience, 505 Parnassus Ave., M-779, 
      San Francisco, CA 94143-0112.
FAU - Cotter, Jennifer
AU  - Cotter J
AD  - University of California, San Francisco, Department of Pathology, 505 Parnassus 
      Ave., M-551, San Francisco, CA, 94143-0102.
FAU - Perry, Arie
AU  - Perry A
AD  - University of California, San Francisco, Department of Pathology, 505 Parnassus 
      Ave., M-551, San Francisco, CA, 94143-0102.
FAU - Mahindra, Anuj
AU  - Mahindra A
AD  - University of California, San Francisco, Department of Medicine, 505 Parnassus 
      Ave., Box 0324, San Francisco, CA, 94143-0324.
FAU - Glastonbury, Christine M
AU  - Glastonbury CM
AD  - University of California, San Francisco, Department of Radiology and Biomedical 
      Imaging, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.
LA  - eng
GR  - R01 CA166766/CA/NCI NIH HHS/United States
GR  - T32 EB001631/EB/NIBIB NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20140702
PL  - United States
TA  - Clin Imaging
JT  - Clinical imaging
JID - 8911831
RN  - 0 (Immunoglobulin Light Chains)
SB  - IM
MH  - Adult
MH  - Brain/pathology/surgery
MH  - Brain Diseases/*diagnosis/surgery
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - *Immunoglobulin Light Chains
MH  - Magnetic Resonance Imaging/methods
MH  - Paraproteinemias/*diagnosis/surgery
PMC - PMC4854295
MID - NIHMS775036
OTO - NOTNLM
OT  - Amyloidoma
OT  - Light chain deposition disease
OT  - MRI
OT  - Monoclonal immunoglobulin deposition disease
EDAT- 2014/08/03 06:00
MHDA- 2015/06/13 06:00
PMCR- 2016/05/03
CRDT- 2014/08/03 06:00
PHST- 2014/04/11 00:00 [received]
PHST- 2014/06/24 00:00 [revised]
PHST- 2014/06/26 00:00 [accepted]
PHST- 2014/08/03 06:00 [entrez]
PHST- 2014/08/03 06:00 [pubmed]
PHST- 2015/06/13 06:00 [medline]
PHST- 2016/05/03 00:00 [pmc-release]
AID - S0899-7071(14)00164-8 [pii]
AID - 10.1016/j.clinimag.2014.06.015 [doi]
PST - ppublish
SO  - Clin Imaging. 2014 Nov-Dec;38(6):868-71. doi: 10.1016/j.clinimag.2014.06.015. 
      Epub 2014 Jul 2.