PMID- 25087464
OWN - NLM
STAT- MEDLINE
DCOM- 20141113
LR  - 20140911
IS  - 1879-1913 (Electronic)
IS  - 0002-9149 (Linking)
VI  - 114
IP  - 6
DP  - 2014 Sep 15
TI  - Long-term follow-up after pulmonary valve replacement in repaired tetralogy of 
      Fallot.
PG  - 901-8
LID - S0002-9149(14)01370-8 [pii]
LID - 10.1016/j.amjcard.2014.06.023 [doi]
AB  - Surgical pulmonary valve replacement (PVR) in previously repaired tetralogy of 
      Fallot (TOF) is frequently required. There are few data in large series of 
      patients with long-term follow-up. Our aim was to review our 40-year experience 
      with PVR after TOF repair and to evaluate prognostic factors for reintervention 
      and death. Between 1973 and 2012, 278 patients with repaired TOF (53% men; 31.4 +/- 
      16.4 years) underwent first PVR 24 +/- 13 years after TOF repair. Three or more 
      previous operations were performed in 17% of the patients, and 42% were in New 
      York Heart Association (NYHA) class III/IV. PVR types included porcine (n = 211), 
      pericardial (n = 37), homograft (n = 27), and mechanical (n = 3). Early mortality 
      was 1.4%. Mean follow-up was 7.3 +/- 6.8 years (maximum, 34 years). Overall 
      survival at 5, 10, and 15 years was 93%, 83%, and 80% compared with 99%, 97%, and 
      95% in a gender- and age-matched US population, p <0.001. Independent risk 
      factors for death were older age at complete repair (hazards ratio [HR] 1.2, p = 
      0.012), >/= 3 previous cardiac operations (HR 1.9, p = 0.019), NYHA class III/IV at 
      PVR (HR 2.7, p = 0.019), and large body surface area at PVR (HR 1.9, p <0.001). 
      Reintervention after initial PVR occurred in 25 patients. Overall 5, 10, and 15 
      years freedom from pulmonary valve reintervention was 97%, 85%, and 75%, 
      respectively. Multivariate analysis demonstrated older age at PVR to be 
      protective from reintervention (HR 0.7, p <0.001). In conclusion, PVR is a safe 
      operation with a low rate of reintervention in repaired TOF. The total number of 
      cardiac operations, surgical timing, and the NYHA classification before PVR are 
      important prognostic factors.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Sabate Rotes, Anna
AU  - Sabate Rotes A
AD  - Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota; 
      Departament de Pediatria, Universitat Autonoma de Barcelona, Barcelona, Spain.
FAU - Eidem, Benjamin W
AU  - Eidem BW
AD  - Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota.
FAU - Connolly, Heidi M
AU  - Connolly HM
AD  - Division of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota.
FAU - Bonnichsen, Crystal R
AU  - Bonnichsen CR
AD  - Division of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota.
FAU - Rosedahl, Jordan K
AU  - Rosedahl JK
AD  - Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, 
      Minnesota.
FAU - Schaff, Hartzell V
AU  - Schaff HV
AD  - Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
FAU - Dearani, Joseph A
AU  - Dearani JA
AD  - Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
FAU - Burkhart, Harold M
AU  - Burkhart HM
AD  - Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota. Electronic 
      address: burkhart.harold@gmail.com.
LA  - eng
GR  - UL1 TR000135/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20140702
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Adult
MH  - Cardiac Surgical Procedures
MH  - Child, Preschool
MH  - Echocardiography
MH  - Follow-Up Studies
MH  - *Forecasting
MH  - Heart Valve Prosthesis Implantation/*methods
MH  - Humans
MH  - Infant
MH  - Male
MH  - Pulmonary Valve/abnormalities/*surgery
MH  - Reoperation
MH  - Retrospective Studies
MH  - Tetralogy of Fallot/diagnosis/*surgery
EDAT- 2014/08/05 06:00
MHDA- 2014/11/14 06:00
CRDT- 2014/08/05 06:00
PHST- 2014/05/29 00:00 [received]
PHST- 2014/06/10 00:00 [revised]
PHST- 2014/06/10 00:00 [accepted]
PHST- 2014/08/05 06:00 [entrez]
PHST- 2014/08/05 06:00 [pubmed]
PHST- 2014/11/14 06:00 [medline]
AID - S0002-9149(14)01370-8 [pii]
AID - 10.1016/j.amjcard.2014.06.023 [doi]
PST - ppublish
SO  - Am J Cardiol. 2014 Sep 15;114(6):901-8. doi: 10.1016/j.amjcard.2014.06.023. Epub 
      2014 Jul 2.