PMID- 25091722 OWN - NLM STAT- MEDLINE DCOM- 20150615 LR - 20220409 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 176 IP - 2 DP - 2014 Sep 20 TI - Early repolarization is associated with atrial and ventricular tachyarrhythmias in patients with acute ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. PG - 327-32 LID - S0167-5273(14)01073-0 [pii] LID - 10.1016/j.ijcard.2014.06.006 [doi] AB - BACKGROUND: Recent studies found that early repolarization (ER) is significantly more common in survivors of aborted sudden cardiac death. We hypothesized that ER might be more common in patients with ST elevation myocardial infarction (STEMI) who have complications of atrial and ventricular arrhythmias. METHODS: This study included 266 patients with acute STEMI undergoing primary percutaneous coronary intervention. Twelve-lead electrocardiograms were analyzed for ER, defined as J-point elevation >/= 0.1 mV and "notching" and "slurring" of the terminal part of the QRS complex in at least 2 lateral or inferior leads. Acute and late atrial and ventricular arrhythmic events were evaluated. RESULTS: The ER pattern was observed in 76 patients (28.6%). Atrial arrhythmia [21/76 (27.6%) vs. 22/190 (11.6%), p=0.001] and ventricular arrhythmia [16/76 (21.1%) vs. 16/190 (8.4%), p=0.004] were more frequently complicated in patients with ER than those without during hospitalization. ER was a significant independent predictor of developing atrial (HR=2.682, 95% CI=1.355-5.310, p=0.005) and ventricular arrhythmia (HR=2.936, 95% CI=1.360-6.335, p=0.006). Three patients with ER and ventricular fibrillation expired during hospitalization [3.9% (3/76) vs. 0% (0/190), p=0.023]. However, the presence of ER did not affect the late recurrence of atrial and ventricular arrhythmia. CONCLUSIONS: The ER pattern is commonly observed in patients with STEMI and associated with atrial and ventricular tachyarrhythmia during acute setting. CI - Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved. FAU - Park, Yae Min AU - Park YM AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Kang, Woong Chol AU - Kang WC AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Suh, Soon Yong AU - Suh SY AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Lee, Kyunghoon AU - Lee K AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Han, Seung Hwan AU - Han SH AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Shin, Mi-Seung AU - Shin MS AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Koh, Kwang Kon AU - Koh KK AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Ahn, Taehoon AU - Ahn T AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. FAU - Kim, Young-Hoon AU - Kim YH AD - Cardiology Division, Korea University Anam Hospital, Seoul, Korea. FAU - Choi, In Suck AU - Choi IS AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. Electronic address: cis@gilhospital.com. FAU - Shin, Eak Kyun AU - Shin EK AD - Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea. LA - eng PT - Journal Article DEP - 20140618 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Aged MH - Electrocardiography/trends MH - Female MH - Follow-Up Studies MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*diagnosis/epidemiology/physiopathology MH - Percutaneous Coronary Intervention/*trends MH - Retrospective Studies MH - Risk Factors MH - Tachycardia, Supraventricular/*diagnosis/epidemiology/physiopathology MH - Tachycardia, Ventricular/*diagnosis/epidemiology/physiopathology MH - Time Factors OTO - NOTNLM OT - Atrial and ventricular arrhythmia OT - Early repolarization (ER) OT - ST elevation myocardial infarction (STEMI) EDAT- 2014/08/06 06:00 MHDA- 2015/06/16 06:00 CRDT- 2014/08/06 06:00 PHST- 2013/10/07 00:00 [received] PHST- 2014/05/19 00:00 [revised] PHST- 2014/06/09 00:00 [accepted] PHST- 2014/08/06 06:00 [entrez] PHST- 2014/08/06 06:00 [pubmed] PHST- 2015/06/16 06:00 [medline] AID - S0167-5273(14)01073-0 [pii] AID - 10.1016/j.ijcard.2014.06.006 [doi] PST - ppublish SO - Int J Cardiol. 2014 Sep 20;176(2):327-32. doi: 10.1016/j.ijcard.2014.06.006. Epub 2014 Jun 18.