PMID- 25092490
OWN - NLM
STAT- MEDLINE
DCOM- 20150928
LR  - 20161020
IS  - 1741-203X (Electronic)
IS  - 1041-6102 (Linking)
VI  - 27
IP  - 1
DP  - 2015 Jan
TI  - A pilot study: comparative research of social functioning, circadian rhythm 
      parameters, and cognitive function among institutional inpatients, and 
      outpatients with chronic schizophrenia and healthy elderly people.
PG  - 135-43
LID - 10.1017/S1041610214001604 [doi]
AB  - BACKGROUND: Irregular circadian rhythm and cognitive impairment are frequently 
      observed in patients with chronic schizophrenia. However, their effects in 
      different living environments or with aging remain unclear. The aim of this study 
      was to clarify the characteristics of circadian rhythm and cognition function in 
      the patients with chronic schizophrenia. METHODS: This report described data 
      collected using continuous wrist-active monitoring in real-life settings for 
      seven days and the Brief Assessment of Cognition in Schizophrenia Japanese 
      Version (BACS-J) from 10 inpatients with chronic schizophrenia, 10 outpatients 
      with chronic schizophrenia, and 15 healthy elderly people. The Global Assessment 
      of Functioning (GAF) Scale was used to measure the social functioning in the 
      patients with chronic schizophrenia. RESULTS: The outpatients with chronic 
      schizophrenia exhibited highly interrupted circadian patterns in terms of 
      stability and the fragmentation of activity (p < 0.05) as indexed according to 
      Interdaily Stability (IS) and Intradaily Variability (IV). The inpatients with 
      chronic schizophrenia indicated the most stable rhythm (p < 0.05) and inactive 
      state (p = 0.001) among the groups. Also, the inpatients with chronic 
      schizophrenia showed poorer cognitive functioning with Z-scores of subtests 
      except digit sequencing (p < 0.01). According to stepwise linear regression 
      analysis, the motor speed of BACS-J and IS of circadian parameters were the most 
      powerful variables to predict the GAF in patients with chronic schizophrenia. 
      CONCLUSIONS: The characteristics of circadian rhythm and cognition function in 
      the inpatients with chronic schizophrenia appear distinct from those in the 
      outpatients and the healthy elderly people. Circadian rhythm and cognition 
      function in the patients with chronic schizophrenia may, in part, be affected by 
      different living environments.
FAU - Kume, Yu
AU  - Kume Y
AD  - Department of Occupational Therapy,Graduate School of Health Sciences,Akita 
      University,Hondo,Akita,Japan.
FAU - Sugita, Takio
AU  - Sugita T
AD  - Yokote Kohsei Hospital,Negishicho,Yokote,Japan.
FAU - Oga, Kenya
AU  - Oga K
AD  - Yokote Kohsei Hospital,Negishicho,Yokote,Japan.
FAU - Kagami, Kai
AU  - Kagami K
AD  - Akita Higashi Hospital,Yamauchiazamarukibashi,Akita,Japan.
FAU - Igarashi, Hitomi
AU  - Igarashi H
AD  - Kasamatsu Hospital,Hamadaazaainohara,Akita,Japan.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20140805
PL  - England
TA  - Int Psychogeriatr
JT  - International psychogeriatrics
JID - 9007918
SB  - IM
MH  - Aged
MH  - *Circadian Rhythm
MH  - Cognition
MH  - Female
MH  - Humans
MH  - Inpatients/*psychology
MH  - Intelligence Tests
MH  - Male
MH  - *Mental Competency
MH  - Neuropsychological Tests
MH  - Outpatients/*psychology
MH  - Pilot Projects
MH  - Psychiatric Status Rating Scales
MH  - Regression Analysis
MH  - *Schizophrenia/diagnosis/physiopathology
MH  - *Schizophrenic Psychology
EDAT- 2014/08/06 06:00
MHDA- 2015/09/29 06:00
CRDT- 2014/08/06 06:00
PHST- 2014/08/06 06:00 [entrez]
PHST- 2014/08/06 06:00 [pubmed]
PHST- 2015/09/29 06:00 [medline]
AID - S1041610214001604 [pii]
AID - 10.1017/S1041610214001604 [doi]
PST - ppublish
SO  - Int Psychogeriatr. 2015 Jan;27(1):135-43. doi: 10.1017/S1041610214001604. Epub 
      2014 Aug 5.