PMID- 25095424 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150901 LR - 20140806 IS - 1000-0593 (Print) IS - 1000-0593 (Linking) VI - 34 IP - 5 DP - 2014 May TI - [Preparation of nanoparticles-modified silica monolith for on-column surface enhanced Raman spectroscopy]. PG - 1289-92 AB - A novel silica monolith modified with Ag/Au nanoparticles was prepared for the on-column surface enhanced Raman spectroscopy (SERS). The bare monolithic silica column was prepared from in-situ co-condensation of tetraethoxysilane (TMOS) and methyl trimethoxysilane (MTMS) in the presence of polyethylene glycol (PEG) via a sol-gel process in the capillary, and was chemically modified with (3-mercaptopropyl) trimethoxysilane (MTPMS), followed by immobilization of Ag/Au nanoparticles. Transmission electron microscopy (TEM) and UV-Vis spectrometer were used to collect the TEM images and the extinction spectra of the nanoparticles colloid, respectively. Scanning electron microscope (SEM) was utilized to record the morphology of the silica monolith The authros used p-aminothiophenol (PATP) as a probing molecule, and the SERS effect was investigated on Au/Ag nanoparticle-modified silica monolith under the excitation line of 633 and 532 nm, respectively. It is concluded that nanoparticle-modified silica monoliths will have broad application to the on-site detection of food and water contaminants in the field. FAU - Liu, Chan AU - Liu C FAU - Chen, Lei AU - Chen L FAU - Ren, Hua-Hua AU - Ren HH FAU - Zhou, Ji AU - Zhou J LA - chi PT - English Abstract PT - Journal Article PL - China TA - Guang Pu Xue Yu Guang Pu Fen Xi JT - Guang pu xue yu guang pu fen xi = Guang pu JID - 9424805 EDAT- 2014/08/07 06:00 MHDA- 2014/08/07 06:01 CRDT- 2014/08/07 06:00 PHST- 2014/08/07 06:00 [entrez] PHST- 2014/08/07 06:00 [pubmed] PHST- 2014/08/07 06:01 [medline] PST - ppublish SO - Guang Pu Xue Yu Guang Pu Fen Xi. 2014 May;34(5):1289-92.